Results 161 to 170 of about 165,965 (304)

The Effect of GLP-1 Receptor Agonists on Epilepsy: No Appetite for Seizures. [PDF]

Epilepsy Curr
Karakis I.
europepmc   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

GLP-1 receptor agonists and their implications for female reproductive health. [PDF]

Case Rep Womens Health
Eagles E, Simpson B, Makajeva J, Ayuk PT.   +3 more
europepmc   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

GLP-1 Receptor Agonists in Brazil: Landscape of Consumption, Safety and Regulation. [PDF]

Diabetes Obes Metab
Hurtado RL, Amato AA, de Luca Corrêa H, Silveira D.   +3 more
europepmc   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

Are GLP-1 receptor agonists a 'magic bullet' for cancer? [PDF]

Nat Rev Cancer
Hebert JR, Murphy EA, Playdon MC, Makowski L, Ibele AR, Fairman CM, Hofseth LJ.   +6 more
europepmc   +1 more source

Dipeptidyl Peptidase‐4 Inhibitor Use and Risk of Pemphigus Vulgaris and Foliaceus: A Retrospective Cohort Study Using Databases of the Korea National Health Insurance Claims and the National Health Screening Examination

The Journal of Dermatology, EarlyView.
ABSTRACT Although population‐based studies have reported an increased risk of bullous pemphigoid and pemphigus associated with dipeptidyl peptidase‐4 (DPP‐4) inhibitors, there is limited, well‐designed epidemiological evidence for pemphigus vulgaris (PV), which has only been supported by case reports thus far.
Jaein Lee, Jae Hyun Bae, Seokyung Hahn
wiley   +1 more source

The Potential Indirect Impact of GLP-1 Receptor Agonists in the Management of Fibromyalgia. [PDF]

J Clin Med
Quodling N, Carrick FR, Hoffman N, Jemni M.   +3 more
europepmc   +1 more source

Chronic Disease and Disability in the United States: Trends, Inequities, and Imperatives for Policy Reform

The Milbank Quarterly, EarlyView.
Policy Points Position Universal, High‐Quality Education as a Foundational Public Health Strategy. Long‐term health and life expectancy in the United States are shaped more by educational attainment than by any other single factor. Disparities in access to early childhood, K‐12, and higher education perpetuate cycles of chronic disease, economic ...
ALI H. MOKDAD, LAURA DWYER‐LINDGREN, CHRISTOPHER J.L. MURRAY   +2 more
wiley   +1 more source