Results 141 to 150 of about 53,202 (260)

Effect of GLP-1RA Treatment on Adhesion Molecules and Monocyte Chemoattractant Protein-1 in Diabetic Patients with Atherosclerosis

Cardiovascular disease (CVD) remains a prominent cause of global mortality, primarily driven by atherosclerosis. Diabetes mellitus, as a modifiable risk factor, significantly contributes to atherogenesis.
Bogusław Okopień, Marcin Basiak, Michał Kosowski, Marcin Hachuła   +3 more
core   +1 more source

SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic, Jovana Rajkovic, Radmila Novakovic, Javad Sharifi‐Rad, Daniela Calina   +4 more
wiley   +1 more source

Elevated endogenous glucagon‐like peptide‐1 as a novel Alzheimer's disease biomarker associated with neuroinflammation and Aβ pathology

General Psychiatry, Volume 39, Issue 5, October 2026.
ABSTRACT Background Alzheimer's disease (AD), a neurodegenerative disorder, is pathologically defined by the accumulation of amyloid‐β (Aβ) plaques, hyperphosphorylated tau tangles and sustained neuroinflammation. Glucagon‐like peptide‐1 (GLP‐1), originally characterised as an incretin hormone, is also expressed endogenously in the brain.
Jianping Li, Chenhui Ji, Jintao Wang, Jinwen Xiao, Haixia Li, Xinyi Xie, Nan Zhi, Yaying Song, Wenwei Cao, Liling Wang, Jieli Geng, Rujing Ren, Gang Wang   +12 more
wiley   +1 more source

What Do Sugar, Gila Monsters, and the Therapeutic Dance Have in Common With GLP-1RA, Stroke, and Dementia? [PDF]

Neurol Genet
Worrall BB, Ratan RR.
europepmc   +1 more source

Standardized MRI‐Based Quantification of Epicardial Adipose Tissue Volume: Reproducibility and Agreement With Cardiac Computed Tomography

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1052-1063, October 2026.
ABSTRACT Background Epicardial adipose tissue volume (EATV) is increasingly recognized as a cardiometabolic risk marker associated with adverse outcomes. The most established approach for EATV quantification is cardiac computed tomography (CT). MRI offers a radiation‐free alternative allowing simultaneous assessment of myocardial function and tissue ...
Judith Gronwald, Svante S. Gersch, Zoé Böttiger, Clara Hagedorn, Torben Lange, Sören J. Backhaus, Sebastian Kelle, Constanze Schmidt, Karl Toischer, Andreas Schuster, Alexander Schulz   +10 more
wiley   +1 more source

Exposure to GLP-1RA and Risk of Structural Progression in Differentiated Thyroid Cancer. [PDF]

J Clin Endocrinol Metab
Patrizio A, Mauguen A, Fagin JA, Farooki A, Fish SS, Flory J, Newman S, Presswala L, Sabra MM, Tuttle RM, Boucai L.   +10 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Agonists and the Incidence of Atrial Fibrillation in Obese Patients With Heart Failure With Preserved Ejection Fraction and No Diabetes

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Among obese, non‐diabetic patients with HFpEF, GLP‐1 RA therapy was not significantly associated with incident atrial fibrillation but was associated with lower all‐cause mortality. Prospective studies are needed to clarify the potential role of GLP‐1 RAs in AF prevention. ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) reduce
Farah Rassam, Esteban Kosak Lopez, Sarah Sass, Thitiphan Srikulmontri, Evan Isaacs, John Malin, Phuuwadith Wattanachayakul, Olayinka Afolabi‐Brown   +7 more
wiley   +1 more source

Perceived Competence and GLP-1RA Weight Management Engagement: Mixed-Methods Insights From Six Patient Groups. [PDF]

Obesity (Silver Spring)
McElroy JA, Bertarelli I, Maltagliati C, Smith J, DePietro R.   +4 more
europepmc   +1 more source

Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley   +1 more source

Hypoglycemia Reporting in GLP-1RA Trials for Type 1 Diabetes: A Critical Gap That Needs To Be Addressed. [PDF]

Endocrinol Diabetes Metab
Ishtiaq S, Malik ZM, Ahmad AR.
europepmc   +1 more source