Results 181 to 190 of about 38,595 (290)

Sex-Based Differences in SGLT2i and GLP-1RA Use and Mortality in T2DM with Atherosclerotic Cardiovascular Disease. [PDF]

Biomedicines
Vaknin-Assa H, Wolf A, Hilu R, Giladi E, Gabarin M, Losin I, Arnson Y, Pereg D, Assali A, Arow Z.   +9 more
europepmc   +1 more source

Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5834-5847, July 2026.
ABSTRACT Aims To evaluate the associations between semaglutide initiation and long‐term skeletal outcomes in people with obesity, stratified by type 2 diabetes (T2D) status, using target trial emulation. Materials and Methods This retrospective cohort study used the TriNetX federated electronic health record network.
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Shao‐Chia Chen, Hao‐I Hsieh, Gideon Meyerowitz‐Katz, Yen‐Liang Liu, Pen‐Hua Su   +8 more
wiley   +1 more source

Estimated Oral Semaglutide Exposure Has Distinct Relationships With Glycaemic Response, Weight Loss and Gastrointestinal Tolerability

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 6405-6412, July 2026.
ABSTRACT Aims Oral semaglutide absorption is subject to inter‐individual variability. We investigated whether estimated individual exposure (eC avg ) provides predictive information beyond the prescribed dose in a real‐world cohort of patients with type 2 diabetes (T2D).
Gian Paolo Fadini, Mario Luca Morieri, Carlotta Boscaro, Benedetta Maria Bonora, Andrea Cignarella   +4 more
wiley   +1 more source

Perceptions of Glucagon‐like Peptide 1 Receptor Agonists Among Individuals With Knee Osteoarthritis and Excess Weight: A Qualitative Study

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Objective Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) facilitate weight loss and reduce pain among individuals with knee osteoarthritis (OA). We investigated attitudes and barriers influencing GLP‐1RA use among individuals with knee OA and excess weight to draw distinctions in perspectives between patients with and without GLP‐1RA experience ...
Kelly Frier, Madison Dietl, Sasha Aronson, Jon Dhani, Khara James, Daniel Betensky, Faith Selzer, Elena Losina, Jeffrey N. Katz, Jason S. Kim, Nomi S. Weiss‐Laxer   +10 more
wiley   +1 more source

The Proteomic Analysis of Intermittent Fasting Alone or with GLP-1RA in NAFLD Rats. [PDF]

Diabetes Metab Syndr Obes
Shao Y, Xu S, Ma Y, Zhang J, Guo X, Zhang T, Yuan G.   +6 more
europepmc   +1 more source

Reversal of Pacing‐Induced Cardiomyopathy After Upgrade to Left Bundle Branch Area Pacing: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT High‐burden right ventricular pacing induced cardiomyopathy in a 47‐year‐old male; upgrading to left bundle branch area pacing may lead to rapid and sustained recovery of cardiac function.
Mengqi Yeh, Shunsong Chen, Shanshan He, Ke Liu, Kai Yang, Jiang Wang, Zhiying Zhao, Feiyan Shang, Jinrui Guo   +8 more
wiley   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 100-112, June 2026.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 85-99, June 2026.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source

Evaluating Suicidal Risk in GLP-1RA Therapy: An Umbrella Review of Meta-Analytic Evidence. [PDF]

Healthcare (Basel)
Ștefănescu C, Bratu EA, Pelin AM, Boroi D, Crecan-Suciu BD, Ștefănescu V.   +5 more
europepmc   +1 more source

Συστηματική ανασκόπηση: Ο ρόλος των GLP-1RAs στην καρδιαγγειακή νόσο / Systematic review: The role of GLP-1RAs in CVD

Ιστορικό: Οι αγωνιστές του υποδοχέα της γλυκαγόνης-1 (GLP-1RA) είναι καθιερωμένοι παράγοντες μείωσης της γλυκόζης και απώλειας βάρους, ωστόσο το πλήρες καρδιαγγειακό τους δυναμικό παραμένει ασαφές. Σκοπός: Να συντεθεί τεκμηρίωση σχετικά με τις καρδιαγγειακές επιδράσεις των μακράς δράσης GLP-1RA, με έμφαση στις σοβαρές ανεπιθύμητες καρδιαγγειακές ...
openaire   +1 more source