Results 381 to 390 of about 443,164 (406)
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Aging Clinical and Experimental Research, 1995
Information on the role of glucocorticoids in the aging of vertebrate species is reviewed. There is strong evidence that elevated plasma glucocorticoid levels have a causal role in the rapid deterioration following reproduction in semelparous vertebrate species.
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Information on the role of glucocorticoids in the aging of vertebrate species is reviewed. There is strong evidence that elevated plasma glucocorticoid levels have a causal role in the rapid deterioration following reproduction in semelparous vertebrate species.
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1979
Steroids in general and glucocorticoids in particular affect lysosomes in various ways. The explanation of these effects remains in dispute, however. Theories include the view that steroids interact directly with lysosomal membranes, that steroids provoke induced changes in lysosomes, and that classical steroid receptors originate in lysosomes ...
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Steroids in general and glucocorticoids in particular affect lysosomes in various ways. The explanation of these effects remains in dispute, however. Theories include the view that steroids interact directly with lysosomal membranes, that steroids provoke induced changes in lysosomes, and that classical steroid receptors originate in lysosomes ...
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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
Nature, 1980A. Wyllie
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Macrophages and the glucocorticoids
Journal of Neuroimmunology, 1992Macrophages fulfill such functions as (i) housekeeping and scavenging, (ii) protective and defense, and (iii) memory. Glucocorticoids are hormones also used as anti-inflammatory and immuno-suppressive drugs. They act on the many functions of macrophages, mainly by interfering with functions (ii) and (iii).
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2015
The lung is a major clinical target of glucocorticoid-based therapeutics, and GR signaling has broad effects on respiratory physiology and inflammation. During lung development, expression of GR in the mesenchyme is required for normal terminal alveolar epithelial differentiation.
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The lung is a major clinical target of glucocorticoid-based therapeutics, and GR signaling has broad effects on respiratory physiology and inflammation. During lung development, expression of GR in the mesenchyme is required for normal terminal alveolar epithelial differentiation.
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Annales d'Endocrinologie, 2018
Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis and the most frequent cause of osteoporosis in young people. Bone loss and fracture risk increase rapidly after the initiation of corticosteroid therapy and are proportional to dose and treatment duration.
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Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis and the most frequent cause of osteoporosis in young people. Bone loss and fracture risk increase rapidly after the initiation of corticosteroid therapy and are proportional to dose and treatment duration.
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Endocrinology and Metabolism Clinics of North America, 1994
Glucocorticoids alter the host response to both common and unusual infectious agents through widespread effects on immunity and the inflammatory process. Patients with ectopic ACTH syndrome or with exposure to high doses of exogenous glucocorticoids are at highest risk of infection.
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Glucocorticoids alter the host response to both common and unusual infectious agents through widespread effects on immunity and the inflammatory process. Patients with ectopic ACTH syndrome or with exposure to high doses of exogenous glucocorticoids are at highest risk of infection.
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Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity
Nature Network Boston, 2019H. Yang +26 more
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