Results 171 to 180 of about 174,209 (261)

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo, Ao‐Ying Li, Ting‐Ting Xiang, Zu‐Hao Zhang, Ao Deng, Yang Han   +5 more
wiley   +1 more source

Acute Hemolytic Anemia Due to Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Triggered by Helicobacter pylori Quadruple Therapy in a Jehovah's Witness: A Case Report. [PDF]

Cureus
Dhami AS, Koladiya P, Sahhar F.
europepmc   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

A clinical algorithm to identify people with the glucose-6-phosphate dehydrogenase p.Val68Met variant at risk for diabetes undertreatment. [PDF]

Genet Med Open
Pershad Y, Breeyear JH, Corty RW, Mosley JD, VA Million Veteran Program, Phillips LS, Giri A, Roden DM, Edwards TL, Bick AG.   +9 more
europepmc   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Upadacitinib-Induced Hemolysis in a Patient With Glucose-6-Phosphate Dehydrogenase Deficiency-A Possible Adverse Drug Reaction. [PDF]

Pharmacol Res Perspect
Patanè L, Costantino G, Muscianisi M, De Francesco C, Viola A, Fries W.   +5 more
europepmc   +1 more source

Bacillus subtilis Mobilizes Phosphorus by Reshaping P Pools, Sorption, and Enzyme Activities

Land Degradation &Development, EarlyView.
ABSTRACT Low phosphorus (P) availability constrains crop production in saline‐alkaline soils of Xinjiang, China. We tested whether Bacillus subtilis (B. subtilis) mobilizes soil P by altering P fractions, sorption–desorption, and P‐cycling enzymes in a saline‐alkaline cotton soil. Under conventional fertilization, B. subtilis was applied at 0 (B0), 15 (
Haiping Xie, Wenbin Deng, Yiming Zhao, Rongjiang Yao, Guangming Liu, Jinlin Chen   +5 more
wiley   +1 more source

Resolving haplotypes of the glucose-6-phosphate dehydrogenase gene using long-range polymerase chain reaction and Oxford Nanopore sequencing. [PDF]

Biol Methods Protoc
Chamchoy K, Jacob BAC, Boonyuen U.
europepmc   +1 more source

Exometabolomics Reveals Metabolic Modulation Induced by Chia Oil Supplementation in Adipose Tissue Explants From Obese Mice

Lipids, EarlyView.
The experimental design and the exometabolomic findings obtained by 1H‐NMR analysis of conditioned media from subcutaneous (SAT) and epididymal adipose tissue (EAT) explants of control and obese mice supplemented with chia oil (1.5% (w/w)). Following 8 weeks of control or high‐fat diet and 5 weeks of chia oil supplementation, SAT and EAT explants were ...
Gilson Costa dos Santos Jr, Agatha Assis‐Ferreira, Gabrielly Muniz‐Cassuce, Tatiana El Bacha, Christina Barja‐Fidalgo, Simone Vargas da Silva   +5 more
wiley   +1 more source

A Male Child With Combined Glucose-6-Phosphate Dehydrogenase Deficiency and Hereditary Elliptocytosis: The First Case Reported From Saudi Arabia. [PDF]

Cureus
Alasmari BG, Al Munajjim FF, Wafa S, Abualama A, Elzubair L.   +4 more
europepmc   +1 more source