Results 11 to 20 of about 302,059 (295)

Ketogenic Diet for Seizure Management in Glucose Transporter Type 1 Deficiency Syndrome: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Glucose transporter Type 1 (GLUT1) deficiency syndrome is a rare genetic disorder impairing glucose transport across the blood-brain barrier, leading to reduced brain glucose availability and neurological symptoms, including epilepsy. The Ketogenic Diet (
Soma Basu, Ranjith Kumar Manokaran, Arambakkam Janardhanam Hemamalini   +2 more
doaj   +2 more sources

Clinical Aspects of Glucose Transporter Type 1 Deficiency: Information From a Global Registry. [PDF]

JAMA Neurol, 2017
Hao J, Kelly DI, Su J, Pascual JM.
europepmc   +2 more sources

The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing. [PDF]

, 2014
Intestinal glucose absorption is mediated by SGLT1 whereas GLUT2 is considered to provide basolateral exit. Recently, it was proposed that GLUT2 can be recruited into the apical membrane after a high luminal glucose bolus allowing bulk absorption of ...
Daniel, H., Geillinger, K.E., Koepsell, H., Röder, P.V., Thorens, B., Zietek, T.S.   +5 more
core   +22 more sources

Structural biology workflow for the expression and characterization of functional human sodium glucose transporter type 1 in Pichia pastoris. [PDF]

Sci Rep, 2019
Suades A, Alcaraz A, Cruz E, Álvarez-Marimon E, Whitelegge JP, Manyosa J, Cladera J, Perálvarez-Marín A.   +7 more
europepmc   +3 more sources

Assessing glucose uptake through the yeast hexose transporter 1 (Hxt1). [PDF]

PLoS ONE, 2015
The transport of glucose across the plasma membrane is mediated by members of the glucose transporter family. In this study, we investigated glucose uptake through the yeast hexose transporter 1 (Hxt1) by measuring incorporation of 2-NBDG, a non ...
Adhiraj Roy, Angela D Dement, Kyu Hong Cho, Jeong-Ho Kim   +3 more
doaj   +1 more source

The Efficacy and Safety of the Combination Therapy With GLP-1 Receptor Agonists and SGLT-2 Inhibitors in Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis

Frontiers in Pharmacology, 2022
Aims: Glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors play a key role in the treatment of type 2 diabetes mellitus.
Chen Li, Chen Li, Jie Luo, Jie Luo, Mingyan Jiang, Mingyan Jiang, Keke Wang, Keke Wang   +7 more
doaj   +1 more source

Effect of duodenal-jejunal bypass on diabetes in the early postoperative period

Scientific Reports, 2023
Metabolic surgery is an effective treatment for patients with type 2 diabetes mellitus (T2DM). The aim of this study was to investigate the effect of duodenal-jejunal bypass (DJB) in a rat model of T2DM during the early postoperative period.
Shohei Okikawa, Hideya Kashihara, Mitsuo Shimada, Kozo Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Chie Takasu, Yuma Wada, Toshiaki Yoshimoto   +8 more
doaj   +1 more source

Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects.
Manoja K. Brahma, Chae‐Myeong Ha, Mark E. Pepin, Sobuj Mia, Zhihuan Sun, John C. Chatham, Kirk M. Habegger, Evan Dale Abel, Andrew J. Paterson, Martin E. Young, Adam R. Wende   +10 more
doaj   +1 more source

A Different SLC2A1 Gene Mutation in Glut 1 Deficiency Syndrome: c.734A>C

Balkan Medical Journal, 2017
Background: Glucose transporter type 1 deficiency syndrome is the result of impaired glucose transport into the brain. Patients with glucose transporter type 1 syndrome may present with infantile seizures, developmental delay, acquired microcephaly ...
Rüya Çolak, Senem Alkan Özdemir, Ezgi Yangın Ergon, Mehtap Kağnıcı, Şebnem Çalkavur   +4 more
doaj   +1 more source

Posttranslational modifications of GLUT4 affect its subcellular localization and translocation [PDF]

, 2013
The facilitative glucose transporter type 4 (GLUT4) is expressed in adipose and muscle and plays a vital role in whole body glucose homeostasis. In the absence of insulin, only ~1% of cellular GLUT4 is present at the plasma membrane, with the vast ...
Bayer, Begum, Birnbaum, Bogan, Bogan, Bogan, Bryant, Cassie Welburn, Chang, Fujita, Garvey, Gill, Giorgino, Govers, Grasbon-Frodl, Gwyn Gould, Haga, Hardy, Herrmann, Hicke, Huang, Ing, James, James, Jessica Sadler, Jeyaraj, Karylowski, Kupriyanova, Lamb, Lau, Lawrence, Lawrence, Leto, Li, Liu, Livingstone, Mahajan, Marsh, Marshall, Marshall, Martin, Matunis, McCormick, Muller, Nia Bryant, Perera, Pessin, Pilch, Piper, Ren, Reusch, Saltiel, Semiz, Shi, Shi, Stöckli, Toh, Urbe, Vannucci, Varki, Watson, Williams, Yang, Yu, Zaarour   +64 more
core   +3 more sources