Results 291 to 300 of about 275,720 (332)

Impaired glucose transport into the brain: the expanding spectrum of glucose transporter type 1 deficiency syndrome

Current Opinion in Neurology, 2004
Glucose transporter type 1 deficiency syndrome (OMIM 606777) is a treatable epileptic encephalopathy resulting from impaired glucose transport into the brain. In recent years, the increasing number of patients has generated substantial insights into the manifestations and mechanisms of this disease.
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Blood-to-brain glucose transport and cerebral glucose metabolism are not reduced in poorly controlled type 1 diabetes.

Diabetes, 1998
To test the hypothesis that blood-to-brain glucose transport is reduced in poorly controlled type 1 diabetes, we studied seven patients with a mean (+/- SD) HbA1c level of 10.1 +/- 1.2% and nine nondiabetic subjects during hyperinsulinemic, mildly hypoglycemic (approximately 3.6 mmol/l, approximately 65 mg/dl) glucose clamps.
FANELLI, Carmine Giuseppe, DENCE CS, MARKHAM J, VIDEEN TO, PARAMORE DS, CRYER PE, POWERS WJ   +6 more
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Glucose transporter type 1 deficiency: a study of two cases with video-EEG

European Journal of Pediatrics, 1999
Glucose transporter type 1 (GLUT1) deficiency is an inborn error of glucose transport. Clinical manifestations are presumed secondary to reduced glucose transport across the blood brain barrier, and include seizures, abnormal tone, developmental delay and hypoglycorrhachia.
P. R. Kollros, S. Mofidi, E. J. Novotny, M. R. Seashore, W. G. Mitchell, Richard G. Boles   +5 more
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Selective inhibition by ethanol of the type 1 facilitative glucose transporter (GLUT1).

Molecular Pharmacology, 1994
Ethanol appears to modulate the function of selective mammalian receptors and transporters by interacting with highly specific membrane protein sites. Of the multiple types of nucleoside transporters known to be present in mammalian cells, we observed that ethanol inhibits only one class of facilitative nucleoside transporters, that inhibited by ...
S W, Krauss, I, Diamond, A S, Gordon
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Association of glucose transporter 1 polymorphisms with type 2 diabetes in the Tunisian population

Diabetes/Metabolism Research and Reviews, 2008
AbstractBackgroundT2DM is a complex metabolic disease. Genetic studies on T2DM have been of little help so far because several genetic association studies have shown conflicting results. In this study, we report the findings of a case‐control study on three SNPs in the GLUT1 gene.
Mohamed Abid, M.-Z. Boudawara, N. Hamza, Claude Granier, F. Jarraya, N. Rekik, Ahmed Rebai, H. Ayadi, K. Makni, Fatma Mnif   +9 more
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Alternative ketogenic diets in glucose transporter type 1 deficiency syndrome

Developmental Medicine & Child Neurology, 2016
This commentary is on the original article by Amalou et al. on pages 1193–1199 of this issue.
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Acute hyperglycemia produces transient improvement in glucose transporter type 1 deficiency

Annals of Neurology, 2010
AbstractObjectiveGlucose transporter type 1 deficiency syndrome (Glut1‐DS) is characterized clinically by acquired microcephaly, infantile‐onset seizures, psychomotor retardation, choreoathetosis, dystonia, and ataxia. The laboratory signature is hypoglycorrhachia.
Cigdem I. Akman, Dong Wang, Linda D. Leary, Dorcas Koenigsberger, Paivi M. Ullner, Kristin Engelstad, Veronica J. Hinton, Darryl C. De Vivo   +7 more
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Glucose Transporter Type 1 Deficiency Syndrome Effectively Treated with Modified Atkins Diet [PDF]

Neuropediatrics, 2013
This is a report on the successful treatment of a 6-year-old girl with genetically proven glucose transporter type 1 deficiency syndrome (GLUT1-DS) with modified Atkins diet (MAD). GLUT1-DS is an inborn disorder of glucose transport across the blood-brain barrier, which leads to energy deficiency of the brain with a broad spectrum of neurological ...
S Baumgartner, Sabine Scholl-Buergi, Edda Haberlandt, Kevin Rostasy, Matthias Baumann, Sibylle Zotter, Veronika Jud, Daniela Karall   +7 more
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Determination of specific interactions between glucose ligand carrying polymer and glucose transporter type‐1 (GLUT‐1) using different cell types

Journal of Biomedical Materials Research Part A, 2003
AbstractIn order to develop a biomimetic polymer for cell recognition, poly [3‐O‐(4′‐vinylbenzyl)‐D‐glucose] (PVG) and different types of glucose transport (GLUT)‐carrying cells, namely, HepG2 cells (GLUT‐1), 3T3‐L1 fibroblast cells (GLUT‐1 and GLUT‐4), and MIN6 cells (GLUT‐2), were tested for specific interaction.
Phill-Houng Choung, Na-Ra Kang, Byung-Moo Min, Jong Hoon Chung, Keun-Hong Park, Eun-Seok Kim, Yun-Hoon Choung, Jeong-Hwa Baek, Il-Hyuk Chung, Byong-Moo Seo, Toshihiro Akaike, Jong-Rak Hong   +11 more
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Phenotypic Spectrum of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

Current Neurology and Neuroscience Reports, 2013
Glut1 deficiency syndrome (Glut1 DS) was originally described in 1991 as a developmental encephalopathy characterized by infantile onset refractory epilepsy, cognitive impairment, and mixed motor abnormalities including spasticity, ataxia, and dystonia. The clinical condition is caused by impaired glucose transport across the blood brain barrier.
Kristin Engelstad, Cigdem I. Akman, Darryl C. De Vivo, Toni S. Pearson, Veronica J. Hinton   +4 more
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