Data on ethyl glucuronide and cocaethylene concentrations in the hair of cocaine users
Data in Brief, 2018 We present data on ethyl glucuronide and cocaethylene concentrations from the hair of cocaine users. Head hair from 64 subjects, previously tested for cocaine, cocaethylene, benzoylecogonine and anhydroecgonine methyl ester (AEME), were subsequently ...
Richard Paul, Lolita Tsanaclis
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Molecules, 2023 Diosmin is used to relieve chronic venous disease (CVD) symptoms. This study aimed to investigate the anti-inflammatory and antioxidant effects of diosmetin-3-O-β-d-glucuronide, the major metabolite of diosmin, using human skin explants.
Sylvie Boisnic +5 more
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Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model. [PDF]
, 2011 The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice engrafted with the human t(4;11) ALL SEM cell line.
Ducore, Jonathan M +5 more
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Journal of Analytical Methods in Chemistry, 2015 In this study, a sensitive, precise, and accurate HPLC-UV method was developed and validated to simultaneously determine the six analytes (luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D ...
Ning Yu +5 more
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The Role of Uptake and Efflux Transporters in the Disposition of Glucuronide and Sulfate Conjugates
Frontiers in Pharmacology, 2022 Glucuronidation and sulfation are the most typical phase II metabolic reactions of drugs. The resulting glucuronide and sulfate conjugates are generally considered inactive and safe.
Erkka Järvinen +6 more
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Non-targeted LC-MS based metabolomics analysis of the urinary steroidal profile [PDF]
, 2017 The urinary steroidal fraction has been extensively explored as non-invasive alternative to monitor pathological conditions as well as to unveil the illicit intake of pseudo-endogenous anabolic steroids in sport.
Botrè, Francesco +3 more
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Chemical synthesis of all-trans retinoyl beta-glucuronide.
Journal of Lipid Research, 1985 All-trans retinoyl fluoride reacts with the 3,6-lactone of glucuronic acid in slightly alkaline solution to give the lactone of retinoyl beta-glucuronide, along with other retinoyl glucurono-lactones, in about 60% yield.
A B Barua, J A Olson
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Use of Urinary Pregnanediol 3-glucuronide to Confirm Ovulation [PDF]
, 2013 Objective Urinary hormonal markers may assist in increasing the efficacy of Fertility Awareness Based Methods (FABM). This study uses urinary pregnanediol-3a-glucuronide (PDG) testing to more accurately identify the infertile phase of the menstrual cycle
Boehringer, H. +6 more
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Journal of Lipid Research, 1989 Biliary secretion of bile acid glucuronides was studied in control rats and in rats with a congenital defect in hepatobiliary transport of organic anions (GY rats).
F Kuipers +6 more
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Validation of a rapid and sensitive LC-MS/MS method for determination of exemestane and its metabolites, 17β-hydroxyexemestane and 17β-hydroxyexemestane-17-O-β-D-glucuronide: application to human pharmacokinetics study. [PDF]
PLoS ONE, 2015 A novel, rapid and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was developed and validated for the evaluation of exemestane pharmacokinetics and its metabolites, 17β-dihydroexemestane (active metabolite) and 17β ...
Ling-Zhi Wang +8 more
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