Results 41 to 50 of about 119,272 (313)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Management of complication during bronchial artery aneurysm embolization
Saudi Journal of Radiology, 2022 Purpose: To report our management technique of glue reflux occurring during embolization of a bronchial artery aneurysm. Case Report: A 68-year-old Chinese male patient presented with an asymptomatic 1.5cm bronchial artery aneurysm, for which he
Rugaiyah Alkhatib +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Prevalence of glue‐sniffing among street children
Nursing Open, 2020 Aim The aim was to determine the prevalence of glue‐sniffing among street children. Design A descriptive cross‐sectional study design was adopted. Background Children are the source of hope and could be the major ailments for the development of society ...
Sanjay Kumar Sah +4 more
doaj +1 more source
Embolization using warmed glue via the triaxial microballoon occlusion system for various vascular disorders [PDF]
, 2020 PURPOSE:We aimed to illustrate the benefits of using warmed glue for viscosity reduction via the triaxial microballoon system for the treatment of various vascular disorders.METHODS:Seven patients who underwent 10 treatment sessions for hemoptysis, type ...
Tatsuo Ueda +4 more
core +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Hydrogel Sealant for Closure of Clear Corneal Incisions in Combined Glaucoma Procedures
Clinical Ophthalmology, 2022 Ryan D Machiele,1 Abhilash Guduru,2 Leon W Herndon2 1Department of Ophthalmology, University of North Carolina, Chapel Hill, NC, USA; 2Department of Ophthalmology, Duke University Medical Center, Durham, NC, USACorrespondence: Leon W Herndon, Department ...
Machiele RD, Guduru A, Herndon LW
doaj
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Annual Review of Linguistics, 2012 Glue Semantics (Glue) is a general framework for semantic composition and the syntax–semantics interface. The framework grew out of an interdisciplinary collaboration at the intersection of formal linguistics, formal logic, and computer science. Glue assumes a separate level of syntax; this can be any syntactic framework in which syntactic structures ...
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source