Results 311 to 320 of about 216,468 (357)

SEPARATION OF GLUTAMINE SYNTHETASE AND GLUTAMYLTRANSFERASE IN RAT TISSUES.

, 1972
Annemarie Herzfeld
openalex   +2 more sources

Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform

Physiological Reports, Volume 13, Issue 19, October 2025.
Abstract Circulating blood cells such as platelets represent a readily available sample type to determine mitochondrial function in humans. Here, we set out to determine the influence of sample preparation, assay buffer composition, and instrumental platform on the respiratory function of platelets isolated from human blood.
Craig Porter, Lillie Treas, Oleksandra Pavliv, Daniel Sadler, Matthew Cotter, Shannon Rose, Elisabet Børsheim, Eva C. Diaz Fuentes   +7 more
wiley   +1 more source

2-oxoglutarate triggers assembly of active dodecamericMethanosarcina mazeiglutamine synthetase

Herdering E, Reif-Trauttmansdorff T, Kumar A, Habenicht T, Hochberg G, Bohn S, Schuller J, Schmitz RA.   +7 more
europepmc   +1 more source

Long non-coding RNA PXN-AS1 promotes glutamine synthetase-mediated chronic myeloid leukemia BCR::ABL1-independent resistance to Imatinib via cell cycle signaling pathway. [PDF]

Cancer Cell Int
Li Y, Yuan S, Zhou Y, Zhou J, Zhang X, Zhang P, Xiao W, Zhang Y, Deng J, Lou S.   +9 more
europepmc   +1 more source

UEG Week 2025 Moderated Posters

United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley   +1 more source

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis [PDF]

Nature, 2018
Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, but surprisingly shows negligible glutamine-synthesizing activity in these cells at physiological glutamine levels.
G. Eelen, Charlotte Dubois, A. Cantelmo, J. Goveia, Ulrike Brüning, M. DeRan, G. Jarugumilli, J. Rijssel, G. Saladino, Federico Comitani, A. Zecchin, Susana Rocha, Rongyuan Chen, Hongling Huang, Saar Vandekeere, Joanna Kalucka, Christian Lange, F. Morales-Rodríguez, B. Cruys, Lucas Treps, L. Ramer, S. Vinckier, K. Brepoels, S. Wyns, Joris Souffreau, L. Schoonjans, W. Lamers, Yi Wu, J. Haustraete, J. Hofkens, S. Liekens, R. Cubbon, B. Ghesquière, M. Dewerchin, F. Gervasio, Xuri Li, J. D. Buul, Xu Wu, P. Carmeliet   +38 more
semanticscholar   +5 more sources

Dysregulation of glutaminase and glutamine synthetase in cancer.

Cancer Letters, 2019
Besides fast glucose catabolism, many types of cancers are characterized by elevated glutamine consumption. Medical oncology pursuits to block specific pathways, mainly glycolysis and glutaminolysis, in tumor cells to arrest cancer development. This strategy frequently induces adaptive metabolic resistance that must be countered. Combination therapy is
J. Matés, José A. Campos-Sandoval, Juan de los Santos-Jiménez, J. Márquez   +3 more
semanticscholar   +6 more sources

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Congenital Glutamine Deficiency with Glutamine Synthetase Mutations

New England Journal of Medicine, 2005
Glutamine synthetase plays a major role in ammonia detoxification, interorgan nitrogen flux, acid-base homeostasis, and cell signaling. We report on two unrelated newborns who had congenital human glutamine synthetase deficiency with severe brain malformations resulting in multiorgan failure and neonatal death.
Annick Toutain, Frank Rutsch, Freimut Schliess, Antoinette Gelot, Dieter Häussinger, Wolfgang Höhne, Jean-François Benoist, Eva Schmidt, Boris Görg, Hans Georg Koch, Annie-Laure Suc, Johannes Häberle   +11 more
openaire   +3 more sources

Localisation of Glutamine Synthetase in Chloroplasts

Nature New Biology, 1973
Glutamine is of considerable importance in plants, as a readily metabolised and translocated intermediate and as a product of ammonia detoxification. Glutamine synthetase carries out the ATP-driven addition of ammonia to glutamate to produce the amide. The source of ATP and information on the metabolic role, for glutamine synthetase may be suggested by
K. W. Joy, D. O'neal
openaire   +3 more sources