Results 331 to 340 of about 216,468 (357)
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Messenger RNA for glutamine synthetase
Molecular and Cellular Biochemistry, 1983Of the various eucaryotic tissues, where glutamine synthetase (GS) mRNA and its regulation have been investigated, the induction of GS by glucocorticoids in the embryonic chick retina represents one of the systems most extensively studied. GS mRNA was first identified at the polysomal level by immunochemical precipitation of fractionated polysomes ...
P K Sarkar, S Chaudhury
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Conversion of glutamic acid to glutamine by retinal glutamine synthetase
Experimental Eye Research, 1973Abstract There is a qualitative correlation within a given retinal tissue between level of glutamine synthetase, as measured by its transferase activity, and ability of the tissue to convert glutamic acid to glutamine in vitro. The present study shows this to be the case for age-dependent endogenous enzyme activity, cortisol-induced enzyme activity ...
Liane Reif-Lehrer +3 more
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The Journal of Biochemistry, 1989
The nucleotide ligation site of adenylylated glutamine synthetase, which contains a unique tyrosyl residue linked through a phosphodiester bond to 5'-AMP, was studied by digestion with three hydrolytic enzymes. The products on micrococcal nuclease digestion were adenosine and o-phosphotyrosyl glutamine synthetase.
Yoshio Nakano +2 more
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The nucleotide ligation site of adenylylated glutamine synthetase, which contains a unique tyrosyl residue linked through a phosphodiester bond to 5'-AMP, was studied by digestion with three hydrolytic enzymes. The products on micrococcal nuclease digestion were adenosine and o-phosphotyrosyl glutamine synthetase.
Yoshio Nakano +2 more
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Glutamine synthetase and transferase
1967This enzyme (or enzymes) catalyzes the following reactions: 1. Glutamate + ATP + NH3 → glutamine + ADP + Pi (glutamine synthesis). 2. Glutamine + NH2OH →γ-glutamylhydroxamate + NH3 (glutamyl transfer reaction). 3. Glutamine + H2O → Glutamate + NH3 (arsenolysis of glutamine).
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Journal of Bacteriology, 1967
The relationships of five feedback inhibitors for the Bacillus licheniformis glutamine synthetase were investigated. The inhibitors were distinguishable by differences in their competitive relationship for the substrates of the enzyme.
E. R. Stadtman, Jerry S. Hubbard
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The relationships of five feedback inhibitors for the Bacillus licheniformis glutamine synthetase were investigated. The inhibitors were distinguishable by differences in their competitive relationship for the substrates of the enzyme.
E. R. Stadtman, Jerry S. Hubbard
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Regulation of Glutamine Synthetase Degradation
1981There is considerable evidence that the synthesis and degradation of proteins is a dynamic process which governs the steady-state level of enzymes in the cell. Although a great deal is known about the factors that regulate the rates of enzyme synthesis, relatively little is known about the mechanism involved in the regulation of enzyme degradation.
Earl R. Stadtman +2 more
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Regulation of glutamine synthetase
Archives of Biochemistry and Biophysics, 1967Abstract Factors influencing subunit association in the glutamine synthetase from Escherichia coli have been studied by means of sucrose gradient sedimentation, disc gel electrophoresis, and light-scattering techniques. The native enzyme is not dissociated by treatments with 0.01 m EDTA, 1.0 m urea, mercaptan, or alkaline pH when tested ...
C.A. Woolfolk, Earl R. Stadtman
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[28] Glutamine synthetase from muscle
1985Publisher Summary The assay for glutamine synthetase activity in muscle measures the rate of synthesis of radioactive glutamine from radioactive glutamate. In muscle, glutamine synthetase plays a biosynthetic role in maintaining the availability of glutamine as a source of nitrogen and as a respiratory or gluconeogenic substrate when dietary sources ...
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[60] Discovery of glutamine synthetase cascade
1990Publisher Summary This chapter describes an experiment carried out to study the intracellular concentration of the enzyme, which could be varied more than 20-fold by variations in the availability of nitrogen in the growth medium. In the experiment, when all eight metabolites were added together, almost complete inhibition of the enzyme activity was ...
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Glutamine synthetase and hepatocarcinogenesis
Carcinogenesis, 1995Rolf Gebhardt, Gary M. Williams
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