Results 301 to 310 of about 77,313 (353)

Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies

MedComm, Volume 6, Issue 6, June 2025.
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen, Yixiao Yuan, Fan Zhou, Lihua Li, Jun Pu, Yong Zeng, Xiulin Jiang   +6 more
wiley   +1 more source

Redox-Sensitive Fluorescent Nanoparticles for Biovisualization of Malignant Tumors. [PDF]

Sovrem Tekhnologii Med
Peltek O, Kopoleva EA, Zyuzin MV.
europepmc   +1 more source

Oxidative Stress in Antigen Processing and Presentation

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang, Yaying Zhang, Xiaojun Liu, Peng Miao, Wenbing Pu, Shanshan Liu, Jing Zhang, Yuan Tian, Guobo Shen, Na Xie   +9 more
wiley   +1 more source

Controlling stimulus sensitivity by tailoring nanoparticle core hydrophobicity.

Biomater Sci
Zhang X, Zhao B, Fu S, Seruya RS, Fanos HE, Petrisor AA, Liu Y, Yang Z, Zhang F.   +8 more
europepmc   +1 more source

The assessment of thiol-disulfide homeostasis and ıschemia-modified albumin levels in patients with acromegaly. [PDF]

Pituitary
Urhan E, Kara CS, Oguz EF, Neselioglu S, Erel O, Altuntas HD, Bayram F.   +6 more
europepmc   +1 more source

Design and evolution of a synthetic small protein scaffold based on the WW domain

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Protein engineering is a powerful tool in biotechnology and the basis to create unprecedented sequences, structures, and functions. The WW domains are a family of naturally occurring proteins involved in the molecular recognition of proline‐rich and phosphorylated peptide sequences with relevance in cellular processes involved in human ...
Ana Margarida Gonçalves Carvalho Dias, Gonçalo Duarte Gomes Teixeira, Arménio Jorge Moura Barbosa, Joao Goncalves, Olga Iranzo, Ana Cecília Afonso Roque   +5 more
wiley   +1 more source

Eco-friendly role of serratia marcescens and pseudomonas fluorescens in enhancing rice growth and mitigating cadmium toxicity via uptake modulation and antioxidant regulation. [PDF]

BMC Plant Biol
Alhaj Hamoud Y, Shaghaleh H, Saleem MH, Alshaharni MO, Alqurashi M, Alhelaify SS, Alharthy OM, Fayad E, Rastogi A.   +8 more
europepmc   +1 more source

Effect of xylitol on low‑density lipoprotein‑stimulated oxidative stress in THP‑1 cells. [PDF]

Mol Med Rep
Huang Z, Li A, Huang R, Shi M, Yang R, Wang W, Huang Z, Liu Y, Wu J.   +8 more
europepmc   +1 more source

Effects of Maternal Obesity on Oxidative Parameters in Maternal and Cord Blood Samples. [PDF]

Cureus
Gok G, Bal C, Desdicioglu R, Yavuz AF, Yilmaz G, Erel Ö.   +5 more
europepmc   +1 more source

Advances in the study of disulfidptosis in digestive tract tumors. [PDF]

Discov Oncol
Chen Y, Zhang D, Yang H, Wu J, He W.
europepmc   +1 more source