Results 91 to 100 of about 87,212 (241)

Irreversible thermal denaturation of human carbonic anhydrase [PDF]

Carbonic Anhydrase (CA; carbonate hydro-lyase, EC 4.2.1.1)), a zinc containing enzyme, catalyzes reversible hydration of carbon dioxide. This metalloenzyme is found in animals, photosynthesizing organisms, and in some nonphotosynthetic bacteria. Thermal
امانی, مجتبی, خدارحمی, رضا, قبادی, سیروس, محرابی, معصومه, موسوی موحدی, علی اکبر   +4 more
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Xanomeline‐Trospium Chloride (Cobenfy): A New Era in Managing Schizophrenia—Comparative Effectiveness and Economic Challenges

Medicine Advances, EarlyView.
Xanomeline‐trospium chloride (cobenfy) is a muscarinic agonist used to treat hallucinations and psychotic illnesses such as Alzheimer's and Schizophrenia. It has been constructed for patients who are unable to tolerate dopamine‐targeting therapies and a comparison is drawn against other similar drugs with variables like cost, mechanism of action ...
Jawairya Muhammad Hussain, Wajiha Arif, Sharjeel Humayun, Nida Shoaib, Saim Mahmood Khan   +4 more
wiley   +1 more source

Pemberian Ekstrak Etanol Daun Salam untuk Menurunkan Ekspresi TGF-β Podosit Glomerulus Tikus Sprague dawley Diabetes Melitus [PDF]

, 2014
Latar Belakang : Diabetes melitus merupakan kelompok sindrom metabolik yang dapat mengakibatkan peningkatan growth factor pada glomerulus, salah satunya yaitu ekspresi TGF-β di podosit.
rumaolat, wiwi
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Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At‐Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers

Molecular Nutrition &Food Research, EarlyView.
Yerba mate intake shows cardiometabolic beneficial effects decreasing blood pressure, blood lipids, inflammatory biomarkers and body fat in healthy and hypercholesterolemic non‐habitual consumers. ABSTRACT Yerba mate has been reported to have antihypertensive, hypocholesterolemic, antidiabetic, or antiobesity properties.
Laura Bravo, Sara Martínez‐López, Jose Luis Sierra‐Cinos, Raquel Mateos, Beatriz Sarriá   +4 more
wiley   +1 more source

Genetic and environmental contributions to the associations between midlife personality and late‐life metabolic health

Obesity, EarlyView.
Abstract Objective Personality traits such as conscientiousness and emotional stability are consistently linked with better metabolic health, but there is limited evidence on the etiology of these associations and their robustness across the life‐span. Methods Therefore, we estimated phenotypic, genetic, and unique environmental associations of traits ...
Colin D. Freilich, Jacob J. Kunkel, Keely A. Dugan, Elise J. Vomacka, Adolfo G. Cuevas, Kristian Markon, Matt McGue, Glenn I. Roisman, Robert F. Krueger   +8 more
wiley   +1 more source

Nutritional priorities to support GLP‐1 therapy for obesity: A joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society

Obesity, EarlyView.
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian, Monica Agarwal, Monica Aggarwal, Lydia Alexander, Caroline M. Apovian, Shagun Bindlish, Jonathan Bonnet, W. Scott Butsch, Sandra Christensen, Eugenia Gianos, Mahima Gulati, Alka Gupta, Debbie Horn, Ryan M. Kane, Jasdeep Saluja, Deepa Sannidhi, Fatima Cody Stanford, Emily A. Callahan   +17 more
wiley   +1 more source

A Study on Proteolytic Enzyme Activity in the Erythrocytes of Diabetic Patients [PDF]

, 2011
The present study demonstrates the possibility of increased proteolytic activities in diabetic individuals. Proteolytic activity was measured by the amount of amino group released by the erythrocyte lysate of the diabetic individual using phenylhydrazine
Bhat, Gopalakrishna P, BS, Varashree
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Towards the Development of a Conceptual Framework of the Determinants of Pre‐eclampsia: A Hierarchical Systematic Review of Biomarkers

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pre‐eclampsia is a leading cause of maternal and perinatal morbidity and mortality. There are several determinants of individual pregnant women's risk of developing pre‐eclampsia, including biomarkers and ultrasound markers. Objective A conceptual framework to collate and summarise the extensive body of literature on biomarkers ...
Terteel Elawad, Hiten D. Mistry, Mai‐Lei Woo Kinshella, Marianne Vidler, Marie‐Laure Volvert, Helen Elwell, Veronique Filippi, Kelly Pickerill, Rachel Craik, Joel Singer, Rosemary Townsend, Hannah Blencowe, Eleni Z. Tsigas, Jeffrey N. Bone, Peter von Dadelszen, Laura A. Magee, the PRECISE Network, Umberto D’Alessandro, Anna Roca, Hawanatu Jah, Andrew Prentice, Melisa Martinez‐Alvarez, Brahima Diallo, Abdul Sesay, Sambou Suso, Baboucarr Njie, Fatima Touray, Yahaya Idris, Fatoumata Kongira, Modou F. S. Ndure, Lawrence Gibba, Abdoulie Bah, Yorro Bah, Marleen Temmerman, Angela Koech, Patricia Okiro, Geoffrey Omuse, Grace Mwashigadi, Mary Goretti Amondi, Consolata Juma, Joseph Mutunga, Moses Mukhanya, Robin Okello, Onesmus Wanje, Isaac Mwaniki, Marvin Ochieng, Emily Mwadime, Esperança Sevene, Corssino Tchavana, Salesio Macuacua, Anifa Vala, Helena Boene, Lazaro Quimice, Sonia Maculuve, Inacio Mandomando, Peter von Dadelszen, Laura A. Magee, Rachel Craik, Marie‐Laure Volvert, Hiten Mistry, Thomas Mendy, Donna Russell, Prestige Tatenda Makanga, Liberty Makacha, Reason Mlambo, Lucilla Poston, Rachel Tribe, Sophie Moore, Tatiana Salisbury, Aris Papageorghiou, Alison Noble, Rachel Craik, Hannah Blencowe, Veronique Filippi, Joy Lawn, Matt Silver, Joseph Akuze, Ursula Gazeley, Judith Cartwright, Guy Whitley, Sanjeev Krishna, Marianne Vidler, Jing Li, Jeff Bone, Mai‐Lei Woo Kinshella, Domena Tu, Ash Sandhu, Kelly Pickerill, Carla Carillho, Benjamin Barratt   +89 more
wiley   +1 more source

Longitudinal changes in peritoneal solute transport rate and the impact of lower glucose degradation product glucose dialysates

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 471-478, June 2025.
Abstract Introduction Peritoneal solute transfer rates (PSTR) are reported to increase with time. Changes in PSTR were reviewed in long‐term peritoneal dialysis (PD) patients to determine whether lower glucose degradation products (low GDP) dialysates prevented an increase in PSTR. Methods PSTR was determined with a 4‐h peritoneal equilibrium test with
Andrew Davenport
wiley   +1 more source

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights Into MFN‐2‐Mediated Changes

Aging Cell, EarlyView.
Changes in mitochondrial structure and dynamics during aging provide a mechanism for the development of age‐related sarcopenia, a condition characterized by muscle mass loss. Through the creation of three‐dimensional models of mitochondria from quadriceps muscle tissue taken from old and young humans, a loss in mitochondrial complexity was observed to ...
Estevão Scudese, Andrea G. Marshall, Zer Vue, Vernat Exil, Benjamin I. Rodriguez, Mert Demirci, Larry Vang, Edgar Garza López, Kit Neikirk, Bryanna Shao, Han Le, Dominique Stephens, Duane D. Hall, Rahmati Rostami, Taylor Rodman, Kinuthia Kabugi, Jian‐qiang Shao, Margaret Mungai, Salma T. AshShareef, Innes Hicsasmaz, Sasha Manus, Celestine N. Wanjalla, Aaron Whiteside, Revathi Dasari, Clintoria R. Williams, Steven M. Damo, Jennifer A. Gaddy, Brian Glancy, Estélio Henrique Martin Dantas, André Kinder, Ashlesha Kadam, Dhanendra Tomar, Fabiana Scartoni, Matheus Baffi, Melanie R. McReynolds, Mark A. Phillips, Anthonya Cooper, Sandra A. Murray, Anita M. Quintana, Nelson Wandira, Okwute M. Ochayi, Magdalene Ameka, Annet Kirabo, Sepiso K. Masenga, Chanel Harris, Ashton Oliver, Pamela Martin, Amadou Gaye, Olga Korolkova, Vineeta Sharma, Bret C. Mobley, Prasanna Katti, Antentor Hinton   +52 more
wiley   +1 more source