Results 91 to 100 of about 73,988 (260)

Clinical Intervention Following Detection of Incident Diabetes Within a Large Psychiatric Service System: A Chart Review Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Individuals with mental illness have a markedly reduced life expectancy, partly due to a significantly increased risk of developing type 2 diabetes, driven by lifestyle factors and the adverse metabolic effects of psychotropic medications.
Pernille Kølbæk, Christopher Rohde, Maria Speed, Henrik Holm Thomsen, Søren Dinesen Østergaard   +4 more
wiley   +1 more source

Cardiometabolic Treatment Gap in Routine Psychiatric Care: A Cross‐Sectional Study of 1553 Patients

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background People with severe mental illness (SMI) have elevated cardiometabolic morbidity and mortality, with similar concerns increasingly reported in other psychiatric conditions including anxiety disorders and ADHD. Somatic conditions are often underdiagnosed and pharmacologically undermanaged in this population.
Vincent Achour, Melanie Faugere, Laurent Boyer, Christophe Lançon, Theo Korchia   +4 more
wiley   +1 more source

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

Andrology, EarlyView.
Abstract Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier, Jann‐Frederik Cremers, Phillip Schrage, Amelie Körtje, Claudia Krallmann, Sabine Kliesch, Jörg Gromoll, Sandra Laurentino, Michael Zitzmann   +8 more
wiley   +1 more source

Triglyceride-glycated hemoglobin index as a superior predictor of type 2 diabetes risk in a large-scale retrospective cohort study

Scientific Reports
Early detection of individuals at elevated risk for type 2 diabetes (T2D) is critical for effective prevention strategies. We developed a novel metabolic marker, the triglyceride-glycated hemoglobin index (TyH-i), which integrates lipid and glycemic ...
Changchun Cao, Yibing Zan, Yong Han, Haofei Hu, Jianjun Long, Yulong Wang   +5 more
doaj   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari, Leonardo Dalla Valentina, Cristina Felicani, Filippo Gabrielli, Simonetta Lugari, Giovanni Corona, Paolo Ventura, Manuela Simoni, Fabio Nascimbeni, Daniele Santi   +9 more
wiley   +1 more source

En face localization of retinal telangiectatic capillaries using OCT compared with ICG angiography in chronic vascular macular oedema

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinal telangiectatic capillaries (TelCaps) are microvascular abnormalities associated with chronic vascular macular oedema and suboptimal response to intravitreal therapy. Targeted laser photocoagulation is beneficial but requires precise localization using indocyanine green angiography (ICG‐A), the reference standard. However, ICG‐A
Lucas Unger, Bénédicte Dupas, Mohamed Bennani, Daniela Castro Farias, Jean‐François Girmens, Aude Couturier, Michel Paques, Marie‐Noëlle Delyfer   +7 more
wiley   +1 more source

Glucagon‐like peptide‐1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions

British Journal of Pharmacology, EarlyView.
Abstract Gastric inhibitory polypeptide (GIP)/Glucagon‐like peptide‐1 (GLP‐1) receptor agonists are increasingly prescribed for the management of obesity and type 2 diabetes, yet research pertinent to their effects on muscle health is limited. Considering the central role of muscle strength as a sarcopenia component, this article summarizes emerging ...
Konstantinos Prokopidis
wiley   +1 more source

Identifying neonatal hyperglycemia thresholds in preterm infants based on retinopathy of prematurity outcomes: proof-of-concept study

Frontiers in Pediatrics
PurposeNeonatal hyperglycemia significantly increases risk for retinopathy of prematurity (ROP) in preterm infants, independent of other major ROP risk factors. However, glucose thresholds predictive of ROP remain undefined.
Tammy Movsas, Tammy Movsas, Claudia Nadernejad, Claudia Nadernejad, Jeannette Prentice, Jeannette Prentice, Brooke Dudick, Amy Pribyl, Lena Sanfilippo, Brooke E. Geddie, Brooke E. Geddie   +10 more
doaj   +1 more source