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Assessment of two glycated hemoglobin immunoassays
Endocrinología, Diabetes y Nutrición (English ed.), 2020Glycated hemoglobin (HbA1c) level reflects chronic glycemic status if reliable tests are used, however, in some regions worldwide high performing assays might not be readily available. This study aimed to asses two HbA1c immunoassays, comparing them with high-performance liquid chromatography (HPLC) assay, three methods available in Ecuador.HbA1c were ...
M, Guadalupe Vargas +10 more
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Fructosamine, glycated hemoglobin, and dietary carbohydrates
Clinica Chimica Acta, 2004Glycated hemoglobin (HbA(1c)), a marker of glycemia in the previous 3 months, was found to be associated with dietary saturated, fat but not with carbohydrates, in recent population surveys. Another nonenzymatically glycated substance in the blood, fructosamine, a marker of glycemia in the previous 3 weeks, is poorly correlated with HbA(1c) in ...
Giovanni Misciagna +2 more
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Structural changes in hemoglobin and glycation
Hemoglobin (Hb) is a hemeprotein found inside erythrocytes and is crucial in transporting oxygen and carbon dioxide in our bodies. In erythrocytes (Ery), the main energy source is glucose metabolized through glycolysis. However, a fraction of Hb can undergo glycation, in which a free amine group from the protein spontaneously binds to the carbonyl of ...Amanda Luise Alves Nascimento +5 more
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Glycated hemoglobin as a marker of cardiovascular risk
Current Opinion in Lipidology, 2006Diabetes mellitus is an established risk factor for cardiovascular disease. This review examines glycated hemoglobin, an indicator of long-term average blood glucose concentrations, in risk prediction for cardiovascular disease.Glycated hemoglobin concentrations predict cardiovascular disease risk in people with diabetes, and trial data suggest that ...
Kay-Tee, Khaw, Nicholas, Wareham
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Determination of glycated hemoglobin by affinity chromatography
Clinica Chimica Acta, 1987An affinity chromatography microcolumn assay for glycated hemoglobin was compared with electrophoretic and microcolumn ion exchange methods. The affinity method has an imprecision of less than 4% for non-diabetic and less than 2% for diabetic specimens.
G, Oremek, U B, Seiffert, G, Schmid
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American Journal of Obstetrics and Gynecology, 1985
Maternal and cord blood glycosylated hemoglobin levels were measured by an affinity chromatographic method in three groups: normal women (nondiabetic women who gave birth to infants that were normal for gestational age); test women (women who had no evidence of glucose intolerance with screening procedures and who gave birth to large-for-gestational ...
R W, Yatscoff, A, Mehta, H, Dean
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Maternal and cord blood glycosylated hemoglobin levels were measured by an affinity chromatographic method in three groups: normal women (nondiabetic women who gave birth to infants that were normal for gestational age); test women (women who had no evidence of glucose intolerance with screening procedures and who gave birth to large-for-gestational ...
R W, Yatscoff, A, Mehta, H, Dean
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Association of glycated hemoglobin with hemoglobin levels in elderly nondiabetic subjects
European Journal of Internal Medicine, 2016Glycated hemoglobin (HgbA1C) is being increasingly used for the diagnosis of diabetes mellitus due to its high availability and reproducibility. Several studies have shown that HgbA1C levels may be affected by levels of hemoglobin and nutritional factors associated with anemia, such as vitamin B12 and iron deficiency.
Alon, Grossman +5 more
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Identification of hemoglobin variants in samples received for glycated hemoglobin testing
Clinica Chimica Acta, 2013In 2010 Singapore's National Health Survey reported 11.3% of the population between 18-69 years of age with diabetes, compared to 8.2% in 2006. This increasing trend reinforces the dependence on HbA(1c) for management of glycemic control.To determine the incidence of hemoglobin variants received from our diabetic population who are attending the ...
Saw, S., Loh, T.P., Yin, C., Sethi, S.K.
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Glycated hemoglobin measurement: intermethod comparison.
Diabetes, nutrition & metabolism, 2001Clinical interpretation of changes in serial measurements of patients' HbA1c ought to be based on the knowledge of pre-analytical, analytical and intra-individual sources of variation that affect the results. The detectable change in HbA1c percentage depends on total analytical error. Since we have previously evidenced major problems in the routine use
MATTEUCCI, ELENA +4 more
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