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Glycated hemoglobin measurement: intermethod comparison.
Diabetes, nutrition & metabolism, 2001Clinical interpretation of changes in serial measurements of patients' HbA1c ought to be based on the knowledge of pre-analytical, analytical and intra-individual sources of variation that affect the results. The detectable change in HbA1c percentage depends on total analytical error. Since we have previously evidenced major problems in the routine use
MATTEUCCI, ELENA +4 more
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Determination of glycated hemoglobin by affinity chromatography
Clinica Chimica Acta, 1987An affinity chromatography microcolumn assay for glycated hemoglobin was compared with electrophoretic and microcolumn ion exchange methods. The affinity method has an imprecision of less than 4% for non-diabetic and less than 2% for diabetic specimens.
G, Oremek, U B, Seiffert, G, Schmid
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Structural changes in hemoglobin and glycation
Hemoglobin (Hb) is a hemeprotein found inside erythrocytes and is crucial in transporting oxygen and carbon dioxide in our bodies. In erythrocytes (Ery), the main energy source is glucose metabolized through glycolysis. However, a fraction of Hb can undergo glycation, in which a free amine group from the protein spontaneously binds to the carbonyl of ...Amanda Luise Alves Nascimento +5 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Assessing the Utility of Glycated Hemoglobin
Diabetes Care, 1998M S, Eberhardt, K M, Flegal
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Glycated Hemoglobin (HbA1c): Pathophysiology and Clinical Significance
International Journal of Health & Medical ResearchDiabetes mellitus has been widely-spread disorder worldwide and it causes a high level of pressure on services provided by health centers. The outcomes of patient can be greatly enhanced by early detection to overcome serious consequences. Glycated hemoglobin (HbA1c) can be utilized to evaluate blood glucose level control over the last three to six ...
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