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Biological variability of glycated hemoglobin

Clinica Chimica Acta, 2010
The measurement of glycated hemoglobin (HbA(1c)) has a pivotal role in monitoring glycemic state in diabetic patients. Furthermore, the American Diabetes Association has recently recommended the use of HbA(1c) for diabetes diagnosis, but a clear definition of the clinically allowable measurement error is still lacking.
F. Braga   +3 more
openaire   +3 more sources

Hemoglobin variants and determination of glycated hemoglobin (HbA1c)

Diabetes/Metabolism Research and Reviews, 2001
Measurement of glycated hemoglobin in diabetic patients is an established procedure for evaluating long-term control of diabetes. The Diabetes Control and Complications Trial (DCCT), as well as the United Kingdom Prospective Diabetes Study (UKPDS), confirmed the direct relationship between the degree of glycemic control as estimated by glycohemoglobin (
Guenter J. Krejs   +4 more
openaire   +3 more sources

Assessment of two glycated hemoglobin immunoassays

Endocrinología, Diabetes y Nutrición (English ed.), 2020
Glycated hemoglobin (HbA1c) level reflects chronic glycemic status if reliable tests are used, however, in some regions worldwide high performing assays might not be readily available. This study aimed to asses two HbA1c immunoassays, comparing them with high-performance liquid chromatography (HPLC) assay, three methods available in Ecuador.HbA1c were ...
M, Guadalupe Vargas   +10 more
openaire   +3 more sources

[5] Purification of glycated hemoglobin

1994
Publisher Summary The term glycohemoglobin (glycated hemoglobin) refers to hemoglobin that has been modified postribosomally by the attachment of glucose to the polypeptide chain. This modification, generically designated nonenzymatic glycation, is a condensation reaction between the carbohydrate and a free amino group at the amino terminus or ɛ ...
Van-Yu Wu, Margo P. Cohen
openaire   +2 more sources

Development of a biosensor for glycated hemoglobin

Electrochimica Acta, 2007
Abstract The development of an electrochemical piezoelectric sensor for the detection of glycated hemoglobin is presented. The total hemoglobin (Hb) content is monitored with a mass-sensitive quartz crystal modified with surfactants, and the glycated fraction of the immobilized Hb is determined by subsequent voltammetric measurement of the coupled ...
Halámek, Jan   +3 more
openaire   +3 more sources

Glycated albumin and glycated hemoglobin levels in normal pregnancy

Biochemical Medicine and Metabolic Biology, 1988
Glycated albumin levels showed a progressive increase during normal pregnancy. The mean values (mole hexose/mole protein) were 1.68 +/- 0.27 (n = 15) in nonpregnant women, 1.83 +/- 0.21 (n = 11) in first trimester, 2.00 +/- 0.41 (n = 13) in second trimester, and 2.42 +/- 0.49 (n = 15) in third trimester.
T. N. Pattabiraman   +2 more
openaire   +3 more sources

Improved Estimation of Glycated Hemoglobin from Continuous Glucose Monitoring and Past Glycated Hemoglobin Data

Diabetes Technology & Therapeutics, 2021
Background: Accurate estimation of glycated hemoglobin (HbA1c) from continuous glucose monitoring (CGM) remains challenging in clinic. We propose two statistical models and validate them in real-life conditions against the current standard, glucose management indicator (GMI).
Beata Mianowska   +7 more
openaire   +3 more sources

Glycated hemoglobin (HbA1c) and outcome following endovascular thrombectomy for ischemic stroke

Journal of NeuroInterventional Surgery, 2019
Background In ischemic stroke, increased glycated hemoglobin (HbA1c) and glucose levels are associated with worse outcome following thrombolysis, and possibly, endovascular thrombectomy.
William K. Diprose   +4 more
semanticscholar   +1 more source

Determination of glycated hemoglobin in clinically silent hemoglobin variants

Diabetes/Metabolism Research and Reviews, 2004
AbstractBackgroundEvaluation of glycated hemoglobin determination methods in patients with clinically silent hemoglobin variants.MethodsHbA1c results were determined with various methods, including a new enzymatic assay, a boronate affinity HPLC, immunoassays and ion‐exchange HPLC in patients with the clinically silent hemoglobin variants Hb Graz, Hb ...
Rainer W. Lipp   +7 more
openaire   +3 more sources

Glycated Hemoglobin as a Measure of Physiological Stress

Behavioral Medicine, 1988
The concentration of glycated hemoglobin (HbA1c) is an integrated expression of the blood glucose concentration level in the previous weeks. The levels of HbA1c were measured in 23 medical students who had to pass an examination within a few weeks. Twelve other students served as a control group. Four months later, the blood tests were repeated.
Bo Netterstrøm   +2 more
openaire   +3 more sources

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