Results 41 to 50 of about 69,722 (292)

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Misleading HbA1c Measurement in Diabetic Patients with Hemoglobin Variants

Medical Sciences, 2021
Background and Objectives: Hemoglobin A1c (HbA1c) is widely used for the monitoring and management of diabetes mellitus. The aim of this study is to investigate the influence of hemoglobin (Hb) variants on the measurement of HbA1c. Materials and Methods:
Manthana Mitchai, Nattakarn Suwansaksri, Suphakdee Seanseeha, Jindamanee Saenboonsiri, Putthichai Kraitree, Jirasak Piyapromdee, Atit Silsirivanit   +6 more
doaj   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

An incidental finding of a hemoglobin E variant in a diabetic patient with an abnormal glycated hemoglobin level: a case report

Journal of Medical Case Reports
Background Glycated hemoglobin is a well-known marker for evaluating long-term glycemic control. However, the accuracy of glycated hemoglobin measurement can be affected by the presence of hemoglobin variants, which makes the determination and ...
Rashmi Karki, Samir Lamichhane, Runa Jha, Rekha Manandhar   +3 more
doaj   +1 more source

Onset of Ulcerative Colitis in a Patient with Type 2 Diabetes: Efficacy of a Plant-Based Diet for Both Diseases

Gastrointestinal Disorders, 2022
No case has been reported in which ulcerative colitis occurred in a patient with type 2 diabetes mellitus and the patient was treated with a plant-based diet.
Mitsuro Chiba, Masafumi Komatsu, Mihoko Hosoba, Kouji Hatano, Masato Takeda   +4 more
doaj   +1 more source

Challenges in Estimation of Glycated Hemoglobin in India [PDF]

Diabetes Technology & Therapeutics, 2013
Glycated hemoglobin (HbA1c) is the most widely accepted index of long-term glycemic control. However, there are some clinical situations that make the accurate measurement of HbA1c difficult. Although some of these situations are general, others are more specific to some parts of the world like India. These conditions include hemoglobinopathies such as
Unnikrishnan, R, Mohan, V
openaire   +3 more sources

Predictive Value of Triglyceride/HDL‐C Ratio for Unplanned Coronary Revascularization in Elderly Patients With Type 2 Diabetes and Coronary Artery Disease: A Retrospective Cohort Study

AGING MEDICINE, EarlyView.
Elevated TG/HDL‐C ratio independently predicted unplanned coronary revascularization in elderly patients with type 2 diabetes and CAD, highlighting its value as a simple and accessible biomarker for long‐term risk stratification. ABSTRACT Objectives The triglyceride‐to‐high‐density lipoprotein cholesterol (TG/HDL‐C) ratio reflects atherogenic ...
Wei Zhu, Yin Zhang, Pan Gao
wiley   +1 more source

Complications in Infants of Diabetic Mothers Related to Glycated Albumin and Hemoglobin Levels During Pregnancy

Pediatrics and Neonatology, 2016
This study was conducted to investigate whether glycated albumin is a useful glycemic marker from the point of view of infant complications for monitoring glycemic control in pregnant women with diabetes or gestational diabetes mellitus.
Daisuke Sugawara, Asami Maruyama, Toshiyuki Imanishi, Yohei Sugiyama, Ko Ichihashi   +4 more
doaj   +1 more source

Predicting three-month fasting blood glucose and glycated hemoglobin changes in patients with type 2 diabetes mellitus based on multiple machine learning algorithms [PDF]

, 2023
Tao Xue, Min Jiang, Yumeng Liu, Qi Hu, Baoqiang Zhu, Jiaqiang Hu, Wenmei Guo, Xingwei Wu, Yu Xiong, Xia Shi, Xueli Zhang, Xu Han, Wenyuan Li, Rongsheng Tong, Enwu Long   +14 more
openalex   +1 more source

Functional Advantage of Central Pancreatectomy Over Distal Pancreatectomy for Benign or Low‐Grade Malignant Tumors: A Comparative Analysis Based on 75‐g Oral Glucose Tolerance Test

Annals of Gastroenterological Surgery, EarlyView.
Central pancreatectomy (CP) better preserves postoperative pancreatic endocrine function than distal pancreatectomy for benign or low‐grade malignant tumors. The 75‐g oral glucose tolerance test demonstrated that CP maintained insulin secretion and glucose tolerance, highlighting its clinical advantage as a function‐preserving procedure.
Dongha Lee, Keiko Kamei, Chihoko Nobori, Yuta Yoshida, Takaaki Murase, Atsushi Takebe, Yuki Okuda, Naru Babaya, Yoshihisa Hiromine, Ippei Matsumoto   +9 more
wiley   +1 more source