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Biological variability of glycated hemoglobin

Clinica Chimica Acta, 2010
The measurement of glycated hemoglobin (HbA(1c)) has a pivotal role in monitoring glycemic state in diabetic patients. Furthermore, the American Diabetes Association has recently recommended the use of HbA(1c) for diabetes diagnosis, but a clear definition of the clinically allowable measurement error is still lacking.
F. Braga   +3 more
openaire   +3 more sources

Diabetes, Glycated Hemoglobin, and Risk of Cancer in the UK Biobank Study

Cancer Epidemiology, Biomarkers and Prevention, 2020
Background: Evidence suggest that diabetes and glycated hemoglobin (HbA1c) levels are associated with cancer risk. However, previous studies have been limited variably by failure to adjust for cancer-specific risk factors (e.g., body mass index ...
R. Peila, T. Rohan
semanticscholar   +1 more source

Hemoglobin variants and determination of glycated hemoglobin (HbA1c)

Diabetes/Metabolism Research and Reviews, 2001
Measurement of glycated hemoglobin in diabetic patients is an established procedure for evaluating long-term control of diabetes. The Diabetes Control and Complications Trial (DCCT), as well as the United Kingdom Prospective Diabetes Study (UKPDS), confirmed the direct relationship between the degree of glycemic control as estimated by glycohemoglobin (
Guenter J. Krejs   +4 more
openaire   +3 more sources

Assessment of two glycated hemoglobin immunoassays

Endocrinología, Diabetes y Nutrición (English ed.), 2020
Glycated hemoglobin (HbA1c) level reflects chronic glycemic status if reliable tests are used, however, in some regions worldwide high performing assays might not be readily available. This study aimed to asses two HbA1c immunoassays, comparing them with high-performance liquid chromatography (HPLC) assay, three methods available in Ecuador.HbA1c were ...
M, Guadalupe Vargas   +10 more
openaire   +3 more sources

Comparison of serum fructosamine and glycated hemoglobin values for assessment of glycemic control in dogs with diabetes mellitus.

American Journal of Veterinary Research, 2020
OBJECTIVE To evaluate the performance of 2 assays for measurement of serum fructosamine (SF) and glycated hemoglobin (HbA1c) values in dogs and to compare the usefulness of the 2 glycated proteins for assessment of glycemic control in dogs with diabetes ...
F. D. Baldo   +10 more
semanticscholar   +1 more source

[5] Purification of glycated hemoglobin

1994
Publisher Summary The term glycohemoglobin (glycated hemoglobin) refers to hemoglobin that has been modified postribosomally by the attachment of glucose to the polypeptide chain. This modification, generically designated nonenzymatic glycation, is a condensation reaction between the carbohydrate and a free amino group at the amino terminus or ɛ ...
Van-Yu Wu, Margo P. Cohen
openaire   +2 more sources

Development of a biosensor for glycated hemoglobin

Electrochimica Acta, 2007
Abstract The development of an electrochemical piezoelectric sensor for the detection of glycated hemoglobin is presented. The total hemoglobin (Hb) content is monitored with a mass-sensitive quartz crystal modified with surfactants, and the glycated fraction of the immobilized Hb is determined by subsequent voltammetric measurement of the coupled ...
Halámek, Jan   +3 more
openaire   +3 more sources

Hemoglobin variants in southern China: results obtained during the measurement of glycated hemoglobin in a large population

Clinical Chemistry and Laboratory Medicine, 2020
Objectives Hemoglobin (Hb) variant is one of the most common monogenic inherited disorders. We aimed to explore the prevalence and hematological and molecular characteristics of Hb variants in southern China.
A. Xu   +4 more
semanticscholar   +1 more source

Glycated albumin and glycated hemoglobin levels in normal pregnancy

Biochemical Medicine and Metabolic Biology, 1988
Glycated albumin levels showed a progressive increase during normal pregnancy. The mean values (mole hexose/mole protein) were 1.68 +/- 0.27 (n = 15) in nonpregnant women, 1.83 +/- 0.21 (n = 11) in first trimester, 2.00 +/- 0.41 (n = 13) in second trimester, and 2.42 +/- 0.49 (n = 15) in third trimester.
T. N. Pattabiraman   +2 more
openaire   +3 more sources

Improved Estimation of Glycated Hemoglobin from Continuous Glucose Monitoring and Past Glycated Hemoglobin Data

Diabetes Technology & Therapeutics, 2021
Background: Accurate estimation of glycated hemoglobin (HbA1c) from continuous glucose monitoring (CGM) remains challenging in clinic. We propose two statistical models and validate them in real-life conditions against the current standard, glucose management indicator (GMI).
Beata Mianowska   +7 more
openaire   +3 more sources

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