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Biological variability of glycated hemoglobin
Clinica Chimica Acta, 2010The measurement of glycated hemoglobin (HbA(1c)) has a pivotal role in monitoring glycemic state in diabetic patients. Furthermore, the American Diabetes Association has recently recommended the use of HbA(1c) for diabetes diagnosis, but a clear definition of the clinically allowable measurement error is still lacking.
F. Braga+3 more
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Diabetes, Glycated Hemoglobin, and Risk of Cancer in the UK Biobank Study
Cancer Epidemiology, Biomarkers and Prevention, 2020Background: Evidence suggest that diabetes and glycated hemoglobin (HbA1c) levels are associated with cancer risk. However, previous studies have been limited variably by failure to adjust for cancer-specific risk factors (e.g., body mass index ...
R. Peila, T. Rohan
semanticscholar +1 more source
Hemoglobin variants and determination of glycated hemoglobin (HbA1c)
Diabetes/Metabolism Research and Reviews, 2001Measurement of glycated hemoglobin in diabetic patients is an established procedure for evaluating long-term control of diabetes. The Diabetes Control and Complications Trial (DCCT), as well as the United Kingdom Prospective Diabetes Study (UKPDS), confirmed the direct relationship between the degree of glycemic control as estimated by glycohemoglobin (
Guenter J. Krejs+4 more
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Assessment of two glycated hemoglobin immunoassays
Endocrinología, Diabetes y Nutrición (English ed.), 2020Glycated hemoglobin (HbA1c) level reflects chronic glycemic status if reliable tests are used, however, in some regions worldwide high performing assays might not be readily available. This study aimed to asses two HbA1c immunoassays, comparing them with high-performance liquid chromatography (HPLC) assay, three methods available in Ecuador.HbA1c were ...
M, Guadalupe Vargas+10 more
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American Journal of Veterinary Research, 2020
OBJECTIVE To evaluate the performance of 2 assays for measurement of serum fructosamine (SF) and glycated hemoglobin (HbA1c) values in dogs and to compare the usefulness of the 2 glycated proteins for assessment of glycemic control in dogs with diabetes ...
F. D. Baldo+10 more
semanticscholar +1 more source
OBJECTIVE To evaluate the performance of 2 assays for measurement of serum fructosamine (SF) and glycated hemoglobin (HbA1c) values in dogs and to compare the usefulness of the 2 glycated proteins for assessment of glycemic control in dogs with diabetes ...
F. D. Baldo+10 more
semanticscholar +1 more source
[5] Purification of glycated hemoglobin
1994Publisher Summary The term glycohemoglobin (glycated hemoglobin) refers to hemoglobin that has been modified postribosomally by the attachment of glucose to the polypeptide chain. This modification, generically designated nonenzymatic glycation, is a condensation reaction between the carbohydrate and a free amino group at the amino terminus or ɛ ...
Van-Yu Wu, Margo P. Cohen
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Development of a biosensor for glycated hemoglobin
Electrochimica Acta, 2007Abstract The development of an electrochemical piezoelectric sensor for the detection of glycated hemoglobin is presented. The total hemoglobin (Hb) content is monitored with a mass-sensitive quartz crystal modified with surfactants, and the glycated fraction of the immobilized Hb is determined by subsequent voltammetric measurement of the coupled ...
Halámek, Jan+3 more
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Clinical Chemistry and Laboratory Medicine, 2020
Objectives Hemoglobin (Hb) variant is one of the most common monogenic inherited disorders. We aimed to explore the prevalence and hematological and molecular characteristics of Hb variants in southern China.
A. Xu+4 more
semanticscholar +1 more source
Objectives Hemoglobin (Hb) variant is one of the most common monogenic inherited disorders. We aimed to explore the prevalence and hematological and molecular characteristics of Hb variants in southern China.
A. Xu+4 more
semanticscholar +1 more source
Glycated albumin and glycated hemoglobin levels in normal pregnancy
Biochemical Medicine and Metabolic Biology, 1988Glycated albumin levels showed a progressive increase during normal pregnancy. The mean values (mole hexose/mole protein) were 1.68 +/- 0.27 (n = 15) in nonpregnant women, 1.83 +/- 0.21 (n = 11) in first trimester, 2.00 +/- 0.41 (n = 13) in second trimester, and 2.42 +/- 0.49 (n = 15) in third trimester.
T. N. Pattabiraman+2 more
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Diabetes Technology & Therapeutics, 2021
Background: Accurate estimation of glycated hemoglobin (HbA1c) from continuous glucose monitoring (CGM) remains challenging in clinic. We propose two statistical models and validate them in real-life conditions against the current standard, glucose management indicator (GMI).
Beata Mianowska+7 more
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Background: Accurate estimation of glycated hemoglobin (HbA1c) from continuous glucose monitoring (CGM) remains challenging in clinic. We propose two statistical models and validate them in real-life conditions against the current standard, glucose management indicator (GMI).
Beata Mianowska+7 more
openaire +3 more sources