Results 141 to 150 of about 444,858 (389)

Impact of a Weekly Glucagon-Like Peptide 1 Receptor Agonist, Albiglutide, on Glycemic Control and on Reducing Prandial Insulin Use in Type 2 Diabetes Inadequately Controlled on Multiple Insulin Therapy: A Randomized Trial [PDF]

, 2020
Julio Rosenstock, Antonio Nino, Joseph Soffer, Lois Erskine, Andre Acusta, Jo Dole, Molly C. Carr, Jason L. Mallory, Philip Home   +8 more
openalex   +1 more source

Glycemic Index (GI) or Glycemic Load (GL) and Dietary Interventions for Optimizing Postprandial Hyperglycemia in Patients with T2 Diabetes: A Review

Nutrients, 2020
The increasing prevalence of type 2 diabetes (T2D) worldwide calls for effective approaches to its management. Strategies for diabetes have generally focused on optimizing overall glycemic control as assessed by glycated hemoglobin (HbA1c) and fasting ...
Dionysios Vlachos, Sofia Malisova, F. Lindberg, Georgia Karaniki   +3 more
semanticscholar   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Glycemic Index and Load of Selected Ethiopian Foods: An Experimental Study

Journal of Diabetes Research, 2019
Background. Determining the glycemic index and load of foods has significant impact on meal planning for diabetes. However, there is no data on the glycemic index (GI) and glycemic load (GL) of Ethiopian foods.
Nebiyu Dereje, Gadise Bekele, Yemisrach Nigatu, Yoseph Worku, Roger P. Holland   +4 more
doaj   +1 more source

Review of Methods for Detecting Glycemic Disorders.

Diabetes Research and Clinical Practice, 2020
Prediabetes (intermediate hyperglycemia) consists of two abnormalities, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) detected by a standardized 75-gram oral glucose tolerance test (OGTT).
M. Bergman, M. Abdul-Ghani, R. DeFronzo, M. Manco, G. Sesti, Teresa Vanessa Fiorentino, A. Ceriello, M. Rhee, L. Phillips, S. Chung, Celeste K L Cravalho, R. Jagannathan, L. Monnier, C. Colette, D. Owens, C. Bianchi, S. Del Prato, M. Monteiro, João Sérgio Neves, José Luiz Medina, M. Paula Macedo, Rogério Tavares Ribeiro, João Filipe Raposo, Brenda Dorcely, Nouran Ibrahim, M. Buysschaert   +25 more
semanticscholar   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 diabetes [PDF]

, 2014
This work was funded by the Chief Scientists Office of the Scottish Government by a joint grant to the University of the Highland and Islands, Grampian Health Board, Biomathematics and Statistics Scotland and the Rowett Institute of Nutrition and Health,
Abraham, Prakash, De Roos, Baukje, Holtrop, Grietje, Johnstone, Alexandra M., Lobley, Gerald E., MacRury, Sandra M., McGeoch, Susan C., Megson, Ian L., O'Kennedy, Niamh, Pearson, Donald W. M., Zhang, Xuguang   +10 more
core   +1 more source

Cockroach‐Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation

Advanced Science, EarlyView.
This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin, Jinchuan Wu, Xiehua Xiao, Xirui Wang, Nianhui Ding, Xin Zhao, Lu Ma, Jie Li, Lunkun Ma, Cehua Ou, Ning Ma, Jianguo Feng   +11 more
wiley   +1 more source

Comparative Effectiveness of DPP-4 Inhibitors Versus Sulfonylurea for the Treatment of Type 2 Diabetes in Routine Clinical Practice: A Retrospective Multicenter Real-World Study [PDF]

, 2018
Introduction: DPP-4 inhibitors (DPP4i) and sulfonylureas are popular second-line therapies for type 2 diabetes (T2D), but there is a paucity of real-world studies comparing their effectiveness in routine clinical practice. Methods: This was a multicenter
Avogaro Angelo, Baldi, Ileana, Bossi, Antonio Carlo, Bottigliengo, Daniele, Cavalot, Franco, D'Angelo, Federica, DARWIN-T2D Network, Fadini, Gian Paolo, Morano S., Raffaella Buzzetti, Zatti, Giancarlo   +10 more
core   +1 more source

Comment on: “GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity”

Advanced Science, EarlyView.
ABSTRACT The recent study by Wang et al. introduces GLM7, a novel composite index integrating routine health indicators to enhance the diagnosis and prediction of multimorbidity. The study provides compelling evidence for the utility of cost‐effective biomarkers in large‐scale health screening.
Yiquan Wang, Tin‐Yeh Huang
wiley   +1 more source