Results 141 to 150 of about 307,887 (342)

Evaluation of endometriosis patients' expectations of a therapeutic patient education program and comparison with practitioners' perception

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Endometriosis significantly affects patients' quality of life, yet its management remains challenging due to diagnostic delays and symptom complexity. Therapeutic patient education (TPE) is effective in chronic disease management, but guidelines are lacking for its application in endometriosis care.
Emma Viteau   +3 more
wiley   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

Temporal response patterns of human gut microbiota to dietary fiber

open access: yesiMeta, EarlyView.
In this study, 19 overweight participants, with or without type 2 diabetes mellitus, underwent 14 days of normal‐diet observation followed by 14 days of dietary fiber intervention. Fecal samples and continuous glucose monitoring data were collected daily throughout the 28‐day period.
Xiaotong Lin   +5 more
wiley   +1 more source

scRiskCell: A single‐cell framework for quantifying islet risk cells and their adaptive dynamics in type 2 diabetes

open access: yesiMeta, EarlyView.
scRiskCell is an interpretable intelligent computational framework that leverages nearly 500,000 islet cell expression profiles from 106 donors across different continuous disease states. By calculating the intrinsic relationship between donor disease states and cell expression profiles, it assigns a pseudo‐cell state index to each cell.
Xueqin Xie   +7 more
wiley   +1 more source

Intranasal Naloxone During Recurrent Exercise in Individuals with Type‐1 Diabetes Mellitus: Evaluation of the Clinical Predictors of Pharmacokinetics and Exposure–Response

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Impaired awareness of hypoglycemia (IAH) impacts 25%–30% of individuals with type 1 diabetes mellitus (T1D), potentially leading to severe outcomes due to reduced symptom perception. Naloxone, a mu‐opioid receptor antagonist, shows promise as a preventive measure against IAH.
Omar N. Al Yacoub   +9 more
wiley   +1 more source

Prevalence, incidence, systemic, behavioral, and patient‐related risk factors and indicators for peri‐implant diseases: An AO/AAP  systematic review and meta‐analysis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background A profound understanding of the epidemiology of peri‐implant diseases (PIDs) is essential for the development of preventive approaches to mitigate the occurrence and progression of peri‐implant biological complications. The present systematic review and meta‐analysis aimed to assess the incidence, prevalence, systemic, behavioral ...
Maria Elisa Galarraga‐Vinueza   +4 more
wiley   +1 more source

Salivary advanced glycated end products, their receptors, and aMMP‐8 in periodontitis patients with varying glycemic levels: A cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Advanced glycation end products (AGE) and their receptors (RAGE) have been implicated in developing periodontal complications in diabetic patients. This study aimed to identify salivary AGE, RAGE, soluble RAGE (sRAGE), and active‐matrix metalloproteinase‐8 (aMMP‐8) levels at varying glycemic levels in periodontitis patients ...
Julie Toby Thomas   +7 more
wiley   +1 more source

Influence of rheumatoid arthritis on peri‐implant diseases: A longitudinal retrospective clinical and radiographic evaluation

open access: yesJournal of Periodontology, EarlyView.
Abstract Background To investigate the effect of rheumatoid arthritis (RA) on the incidence of peri‐implantitis (PI) and peri‐implant mucositis (PIM). Methods Radiographic and clinical chart reviews were conducted to measure the probing depth (PD), bleeding on probing, and marginal bone loss (MBL) around the implants to diagnose peri‐implant diseases ...
Hamzeh Almashni   +4 more
wiley   +1 more source

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