Results 81 to 90 of about 315,758 (337)

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

Advanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding, Yuhuan Jia, Lin Liu, Wen Wang, Danxia Zhou, Zheng Zhou, Likun Yang, Xinyi Chen, Di Chen, Yan Mao, Liwei Xiao, Cai‐Zhi Liu, Zhen‐Yu Du, Yujing Yin, Qiqi Guo, Zongchao Sun, Kai Ge, Tingting Fu, Hai‐Long Piao, Zhenji Gan   +19 more
wiley   +1 more source

Overregulation of Health Care: Musings on Disruptive Innovation Theory [PDF]

, 2006
Disruptive innovation theory provides one lens through which to describe how regulations may stifle innovation and increase costs. Basing their discussion on this theory, Curtis and Schulman consider some of the effects that regulatory controls may have ...
Dahlqvist Leinhard, Olof, Leijon, Göran, Lundberg, Peter, Lundin, Fredrik, Tisell, Anders, Tullberg, M., Wikkelso, C.   +6 more
core   +6 more sources

Effect of probiotics on glycemic control and lipid profiles in patients with type 2 diabetes mellitus: a randomized, double blind, controlled trial

Frontiers in Endocrinology
IntroductionThis double-blind, placebo-controlled, randomized (1:1) clinical trial was conducted at the West China Hospital, Sichuan University, from March to September 2017.MethodsEligible participants included adults aged 18 years and older, living in ...
Xuchao Peng, Hong Xian, Ning Ge, Lisha Hou, Tianjiao Tang, Dongmei Xie, Langli Gao, Jirong Yue   +7 more
doaj   +1 more source

Exploratory analysis of the relationships among different methods of assessing adherence and glycemic control in youth with type 1 diabetes mellitus [PDF]

, 2011
Objectives: The present study examined four methods of assessing diabetes adherence (self-report, diary measure, electronic monitoring, and provider rating) within a population of youth with Type I Diabetes Mellitus (T1DM).
Alemzadeh, Ramin, Kaugars, Astrida S., Kichler, Jessica C., Maglio, Kelly   +3 more
core   +1 more source

Glycemic index and obesity,,, [PDF]

The American Journal of Clinical Nutrition, 2002
Although weight loss can be achieved by any means of energy restriction, current dietary guidelines have not prevented weight regain or population-level increases in obesity and overweight. Many high-carbohydrate, low-fat diets may be counterproductive to weight control because they markedly increase postprandial hyperglycemia and hyperinsulinemia ...
Joanna Mcmillan, Dorota B Pawlak, Janette C. Brand-Miller, Susanna H. A. Holt   +3 more
openaire   +3 more sources

Commentary on “The Impact of Diabetes and Metabolic Syndrome Burden on Pain, Neuropathy Severity and Fiber Type”

Annals of Clinical and Translational Neurology, EarlyView.
Majid Khalilizad, Ebrahim Hejazian, Mohammad Barary, Mostafa Javanian, Soheil Ebrahimpour   +4 more
wiley   +1 more source

Physiological pH Transition‐Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles

Advanced Science, EarlyView.
Physiological pH transitions modulate protein corona dynamics on nanoparticles, altering their cellular uptake and inflammatory responses. Acidic pHs enhance protein adsorption, induce structural changes, and promote cellular uptake. Simultaneously, inflammatory responses are reduced due to altered protein composition, including decreased ...
Yuting Ge, Fangqin Fu, Yu Gao, Tianchang He, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +7 more
wiley   +1 more source

Multi-scale glycemic variability: a link to gray matter atrophy and cognitive decline in type 2 diabetes. [PDF]

PLoS ONE, 2014
Type 2 diabetes mellitus (DM) accelerates brain aging and cognitive decline. Complex interactions between hyperglycemia, glycemic variability and brain aging remain unresolved.
Xingran Cui, Amir Abduljalil, Brad D Manor, Chung-Kang Peng, Vera Novak   +4 more
doaj   +1 more source

Trust and glycemic control in black patients with diabetic retinopathy: A pilot study [PDF]

, 2019
Diabetic retinopathy (DR) is more prevalent in blacks than whites because, compared to whites, blacks on average have worse glycemic control. Both of these racial disparities reflect differences in sociocultural determinants of health, including ...
Casten, Robin J., Rovner, Barry W.
core   +1 more source

Glycemic index and disease,,, [PDF]

The American Journal of Clinical Nutrition, 2002
It has been suggested that foods with a high glycemic index are detrimental to health and that healthy people should be told to avoid these foods. This paper takes the position that not enough valid scientific data are available to launch a public health campaign to disseminate such a recommendation.
openaire   +3 more sources