Results 201 to 210 of about 185,850 (247)
Some of the next articles are maybe not open access.
Glycerol kinase and glycerol utilization in trout (Salmo gairdneri) liver
Comparative Biochemistry and Physiology, 1970Abstract 1. 1. Glycerol kinase (E.C. 2.7.1.30) was found in livers of rainbow trout ( Salmo gairdneri ). The enzyme has a pH optimum of 9·0 and appeared to be more stable at alkaline pH than rat liver glycerol kinase. 2. 2. Liver slices from rainbow trout were able to metabolize glycerol to CO 2 , glycogen and lipids in vitro . 3. 3. In
John J Lech, J J Lech
exaly +3 more sources
Zeitschrift Für Pflanzenphysiologie, 1976
Summary An enzyme which phosphorylates glycerol to sn -glycerol 3-phosphate was studied in leaf extracts using [2- 3 H] glycerol as substrate. The enzyme was found to be a soluble protein of the cytoplasm. In agreement with previous photometric experiments glycerol phosphate dehydrogenase could not be detected in leaf extracts using sn -[2- 3 H ...
E Heinz
exaly +2 more sources
Summary An enzyme which phosphorylates glycerol to sn -glycerol 3-phosphate was studied in leaf extracts using [2- 3 H] glycerol as substrate. The enzyme was found to be a soluble protein of the cytoplasm. In agreement with previous photometric experiments glycerol phosphate dehydrogenase could not be detected in leaf extracts using sn -[2- 3 H ...
E Heinz
exaly +2 more sources
Glycerol homeostasis and metabolism in glycerol kinase carrier mice
Molecular Genetics and Metabolism, 2011To examine glycerol homeostasis and metabolism is essential for understanding of pathogenesis and evaluation of treatment efficacy in disorders of glycerol metabolism. In this study, we designed the intraperitoneal glycerol tolerance test (IPGlyTT) and studied glycerol tolerance in vivo using glycerol kinase (Gyk) carrier (C) and wild type (WT) mice ...
Motomichi Kosuga, Yao-Hua Zhang
exaly +3 more sources
Biochemical and Biophysical Research Communications, 1999
Glycerol kinase (GK) catalyzes the Mg-ATP-dependent phosphorylation of glycerol which yields glycerol 3-phosphate. The 2.8 A new crystal structure of GK complexed with an ATP analog revealed an unexpected position of the gamma-phosphoryl group, which was 7.2 A distant from the 3-hydroxyl group of glycerol, 5.5 A away from the 3-phosphate of the product
exaly +3 more sources
Glycerol kinase (GK) catalyzes the Mg-ATP-dependent phosphorylation of glycerol which yields glycerol 3-phosphate. The 2.8 A new crystal structure of GK complexed with an ATP analog revealed an unexpected position of the gamma-phosphoryl group, which was 7.2 A distant from the 3-hydroxyl group of glycerol, 5.5 A away from the 3-phosphate of the product
exaly +3 more sources
Human Mutation, 2000
Glycerol kinase deficiency has three distinct forms: an isolated form which may be benign or symptomatic, and a complex form which is symptomatic and part of an Xp21 contiguous gene syndrome. Here we report the case of a male with benign isolated glycerol kinase deficiency who was incidentally identified after observation of pseudohypertriglyceridemia.
Bradford L Therrell +2 more
exaly +3 more sources
Glycerol kinase deficiency has three distinct forms: an isolated form which may be benign or symptomatic, and a complex form which is symptomatic and part of an Xp21 contiguous gene syndrome. Here we report the case of a male with benign isolated glycerol kinase deficiency who was incidentally identified after observation of pseudohypertriglyceridemia.
Bradford L Therrell +2 more
exaly +3 more sources
Muscle glycerol kinase in Duchenne dystrophy and glycerol kinase deficiency
Muscle & Nerve, 1989AbstractThe complex glycerol kinase deficiency (GKD) syndrome is an X‐linked recessive genetic disorder. The syndrome often includes a myopathy that is similar histologically to Duchenne muscular dystrophy (DMD). The glycerol kinase (GK) locus is in the Xp21 region in the midportion of the short arm of the X chromosome and is in close proximity to the ...
Seltzer W. K. +4 more
openaire +3 more sources
Glycerol metabolism in higher plants: Glycerol kinase
Biochemical and Biophysical Research Communications, 1987Glycerol kinase activity was identified in extracts of higher plant seeds and seedlings, and was partially purified and characterized from cucumber radicle tissue. The enzyme was localized in the post-mitochondrial supernatant of the cell, and catalyzed the formation of glycerol-3-phosphate. The pH optiumum was 9.0.
D, Sadava, K, Moore
openaire +2 more sources
Adrenal dysfunction in glycerol kinase deficiency
Biochemical Medicine, 1985The infantile form of glycerol kinase deficiency appears to be an X-linked disorder which is consistently characterized by developmental delay and adrenal cortical insufficiency and hypoplasia. We propose that the inherited deficiency of outer mitochondrial membrane-bound glycerol kinase restricts glycerophospholipid synthesis, and, hence, the ...
W K, Seltzer +5 more
openaire +2 more sources
2011
Abstract XLID and slow growth, hypogonadism, spasticity, muscular dystrophy, and osteoporosis associated with hyperglycerolemia, glyceroluria, and glycerol kinase deficiency. The full syndrome is seen only where glycerol kinase deficiency is a component of the contiguous gene syndrome involving adjacent genes for gonadotropin ...
Roger E. Stevenson +2 more
openaire +1 more source
Abstract XLID and slow growth, hypogonadism, spasticity, muscular dystrophy, and osteoporosis associated with hyperglycerolemia, glyceroluria, and glycerol kinase deficiency. The full syndrome is seen only where glycerol kinase deficiency is a component of the contiguous gene syndrome involving adjacent genes for gonadotropin ...
Roger E. Stevenson +2 more
openaire +1 more source