Dihydroxyacetone metabolism in Haloferax volcanii
Frontiers in Microbiology, 2013 Dihydroxyacetone (DHA) is a ketose sugar that can be produced by oxidizing glycerol. DHA in the environment is taken up and phosphorylated to DHA-phosphate by glycerol kinase or DHA kinase.
Matthew eOuellette +2 more
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Renal glycerol metabolism and the distribution of glycerol kinase in rabbit nephron [PDF]
Biochemical Journal, 1981 Glycerol and dihydroxyacetone are metabolized by rabbit kidney-cortex tubules, isolated by collagenase treatment. Half-maximal concentrations of both substrates were determined with regard to uptake rates and product formations. Maximal uptake rates were 643 and 329 mumol/h per g of protein for dihydroxyacetone and glycerol respectively.
G, Wirthensohn +2 more
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Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions. [PDF]
PLoS Pathogens, 2018 The bloodstream forms of Trypanosoma brucei (BSF), the parasite protist causing sleeping sickness, primarily proliferate in the blood of their mammalian hosts.
Erika Pineda +13 more
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Glycerol kinase of Escherichia coli is activated by interaction with the glycerol facilitator [PDF]
Journal of Bacteriology, 1993 Glycerol transport is commonly cited as the only example of facilitated diffusion across the Escherichia coli cytoplasmic membrane. Two proteins, the glycerol facilitator and glycerol kinase, are involved in the entry of external glycerol into cellular metabolism.
R T, Voegele, G D, Sweet, W, Boos
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Glycerol Kinase, the Pacemaker for the Dissimilation of Glycerol in Escherichia coli [PDF]
Journal of Bacteriology, 1970 The activity of glycerol kinase is rate-limiting in the metabolism of glycerol by cells of Escherichia coli . A mutant strain producing a glycerol kinase resistant to inhibition by fructose-1,6-diphosphate grows faster than its wild-type parent on glycerol as the sole source of carbon and energy.
N, Zwaig, W S, Kistler, E C, Lin
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Clinical heterogeneity and novel mutations in the glycerol kinase gene in three families with isolated glycerol kinase deficiency. [PDF]
Journal of Medical Genetics, 1998 Isolated glycerol kinase deficiency (GKD) is an X linked recessive disorder. The clinical and biochemical picture may vary from a childhood metabolic crisis to asymptomatic adult "pseudohypertriglyceridaemia", the result of hyperglycerolaemia. We performed glycerol kinase (GK) gene analysis to study the molecular heterogeneity and genotype-phenotype ...
Sjarif, D. R. +6 more
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A sensitive radioenzymatic assay for glycerol and acylglycerols
Journal of Lipid Research, 1977 A sensitive radioenzymatic assay for glycerol and acylglycerols is described. The assay depends on the quantitative phosphorylation of glycerol to glycerophosphate by glycerol kinase using [γ-32P]ATP as a substrate.
P B Schneider
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Glycerol suppresses glucose consumption in trypanosomes through metabolic contest.
PLoS Biology, 2021 Microorganisms must make the right choice for nutrient consumption to adapt to their changing environment. As a consequence, bacteria and yeasts have developed regulatory mechanisms involving nutrient sensing and signaling, known as "catabolite ...
Stefan Allmann +15 more
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Growth and energy metabolism of Nile tilapia juveniles fed glycerol
Pesquisa Agropecuária Brasileira, 2015 The objective of this work was to evaluate the effect of inclusion of dietary glycerol in replacement to starch on the growth and energy metabolism of Nile tilapia juveniles.
Diego Vicente da Costa +4 more
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Cell Reports, 2019 Summary: The regulation of hepatic gene expression has been extensively studied at the transcriptional level; however, the control of metabolism through posttranscriptional gene regulation by RNA-binding proteins in physiological and disease states is ...
Kostas C. Nikolaou +5 more
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