Results 141 to 150 of about 11,114 (190)

Mechanisms of glyceryl trinitrate provoked mast cell degranulation

Cephalalgia, 2015
BACKGROUND: Migraine patients develop attacks several hours after intravenous infusion of glyceryl trinitrate. Due to the short half-life of nitric oxide, this delayed migraine cannot be caused by a direct action of nitric oxide derived from glyceryl ...
Inger Jansen-Olesen, Jes Olesen, Roshni Ramachandran   +2 more
exaly   +2 more sources

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Thermochemistry of glyceryl trinitrate

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1988
1. Thermochemical investigations of glyceryl trinitrate were carried out to obtain the enthalpy of formation in the standard state, the enthalpy of vaporization, and the enthalpy of formation in the gas phase. 2. The thermodynamic parameters of the intermolecular interactions in liquid glyceryl trinitrate and in solution were evaluated ...
E. A. Miroshnichenko, L. I. Korchatova, V. P. Shelaputina, S. A. Zyuz'kevich, Yu. A. Lebedev   +4 more
openaire   +1 more source

Impotence responsive to glyceryl trinitrate

American Journal of Psychiatry, 1977
The author presents suggestive evidence that glyceryl trinitrate served to treat and diagnose atherosclerotic impotence in a man with psychogenic impotence. The prevalence of atherosclerotic impotence is not known but may be relatively high in older men. Vasodilators may be effective in diagnosing these patients, who do not have clear signs of arterial
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Bioavailability and Pharmacokinetic Profile of Glyceryl Trinitrate and of Glyceryl Dinitrates during Application of a New Glyceryl Trinitrate Transdermal Patch

Arzneimittelforschung, 2011
The pharmacokinetics and bioavailability of glyceryl trinitrate (GTN, CAS 55-63-0) and of its main metabolites, i.e. 1,2-glyceryl dinitrate (1,2-GDN, CAS 621-65-8) and 1,3-glyceryl dinitrate (1,3-GDN, CAS 623-87-0), were compared during a single 24-h application of a new GTN transdermal patch (Epinitril 10, hereinafter called EPI-10) or a reference ...
A, Santoro, L C, Rovati, I, Setnikar, H, Caplain, V, Gualano   +4 more
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Glyceryl trinitrate

Reactions, 1984
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Biotransformation of Glyceryl Trinitrate and Elevation of Cyclic GMP Precede Glyceryl Trinitrate-Induced Vasodilation

Journal of Cardiovascular Pharmacology, 1990
In this study, we examined glyceryl trinitrate (GTN) biotransformation and cyclic GMP elevation in vascular smooth muscle before onset of GTN-induced relaxation. Isolated rabbit aortic strips (RAS) and strips of bovine pulmonary artery (BPA) and bovine pulmonary vein (BPV) were contracted submaximally and incubated with [3H]GTN.
J H, Kawamoto, B E, McLaughlin, J F, Brien, G S, Marks, K, Nakatsu   +4 more
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Toxicity of combinations of glyceryl trinitrate and sympathomimetics

Toxicology and Applied Pharmacology, 1970
Abstract Intraperitoneal injections of glyceryl trinitrate daily for 14 days did not alter the intravenous toxicity of dl-, d-, or l-epinephrine, nor of isoproterenol injected 1–3 days later. There was a decrease in toxicity of dl- or l-epinephrine injected 2 min after glyceryl trinitrate.
D L, Opdyke, C M, Burnett, J C, Munch
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Glyceryl Trinitrate in Angina Pectoris

JAMA, 1964
Despite universal belief in the efficacy of glyceryl trinitrate (nitroglycerin) for the treatment of angina pectoris, some investigators have challenged the validity of clinical impression and declared the drug to be inert. That it is capable of preventing pain as well as ischemic electrocardiographic changes following standard exercise by patients ...
H I, RUSSEK, J C, HOWARD
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Activation of trigeminovascular neurons by glyceryl trinitrate

Brain Research, 2000
The effect of intra-carotid arterial infusions of glyceryl trinitrate (GTN), a substance known to precipitate headache, including migraine, upon the spontaneous activity of trigeminal neurons with craniovascular input was studied in cats. Second-order craniovascular neurons which received sensory input from the superior sagittal sinus were recorded in ...
G A, Lambert, C, Donaldson, P M, Boers, A S, Zagami   +3 more
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ERYTHRODERMA DUE TO PERITRATE AND GLYCERYL TRINITRATE

British Journal of Dermatology, 1972
Summary.— Cutaneous sensitivity to peritrate (pentaerythritol tetranitrate) and glyceryl trinitrate is described, having developed simultaneously, despite the fact that the patient had previously taken drugs without mishap for 10 years.
openaire   +2 more sources