Results 111 to 120 of about 1,881,266 (310)

Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation

Advanced Science, EarlyView.
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan, Ting‐Hui Lee, Tzu‐Ning Peng, Eva Yi‐Hsuan Wu, Yu‐Ting Chiu, Chih‐Chien Chiu, Hong Vinh Nguyen, Yuan‐Shao Pao, Ming‐Hong Chao, Richard Kuan‐Lin Lee, Han‐Chung Wu, Lily Hui‐Ching Wang   +11 more
wiley   +1 more source

Análise da adaptabilidade e estabilidade de linhagens elite de soja - DOI: 10.4025/actasciagron.v26i3.1838

Acta Scientiarum. Agronomy, 2008
Foram analisados os efeitos da interação entre genótipos e ambientes (GxE) sobre a adaptabilidade e a estabilidade do rendimento de 9 linhagens elite de soja (Glycine Max (L.) Merrill) e uma testemunha (IAS 5), observadas em 11 locais em 2000/01 e 2001 ...
Dorival Vicente, Ronald José Barth Pinto, Carlos Alberto Scapim   +2 more
doaj   +1 more source

Max Dupain, self portrait, 1938 [picture] /

, 1938
Title from inscription on reverse.; Condition: Good.; Inscription: "Max Dupain, self portrait, 1938. Printed from the original negative. Jill White, 2001"--Handwritten in ink on reverse.; Part of collection: Max Dupain's life and career, 1929-1992 ...
Dupain, Max, 1911-1992.
core  

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Molecular Analysis of Lipoxygenases Associated with Nodule Development in Soybean

Molecular Plant-Microbe Interactions, 2008
We utilized transcriptional profiling to identify genes associated with nodule development in soybean. Many of the candidate genes were predicted to be involved in processes such as defense, metabolism, transcriptional regulation, oxidation, or iron ...
Satomi Hayashi, Peter M. Gresshoff, Mark Kinkema   +2 more
doaj   +1 more source

Modulation of arsenic-induced oxidative stress and protein metabolism by diphenyleneiodonium, 24-epibrassinolide and proline in Glycine max L.

, 2018
Arsenic (As)-toxicity is a major constraint for crop production. The present study was intended to examine the comparative ameliorative effects of diphenyleneiodonium (DPI), 24-epibrassinolide (EBL) and proline (Pro) on As-stress in Glycine max L.
V. Chandrakar, A. Dubey, S. Keshavkant
semanticscholar   +1 more source

CRISPR/Cas9 and TALENs generate heritable mutations for genes involved in small RNA processing of Glycine max and Medicago truncatula

Plant Biotechnology Journal, 2017
Summary Processing of double‐stranded RNA precursors into small RNAs is an essential regulator of gene expression in plant development and stress response.
Shaun J. Curtin, Yer Xiong, J. Michno, B. Campbell, A. Stec, T. Čermák, Colby G. Starker, D. Voytas, A. Eamens, R. Stupar   +9 more
semanticscholar   +1 more source

A Comparison of Global, Gene-Specific, and Relaxed Clock Methods in a Comparative Genomics Framework: Dating the Polyploid History of Soybean (Glycine max)

, 2010
A Comparison of Global, Gene-Specific, and Relaxed Clock Methods in a Comparative Genomics Framework: Dating the Polyploid History of Soybean (Glycine max) This submission includes the trees for each gene estimated using Penalized Likelihood in r8s ...

core  

Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice. [PDF]

, 2015
Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism. GLDC mutations cause a rare recessive disease non-ketotic hyperglycinemia (NKH).
Brosnan, ME, Greene, ND, Leung, KY, Savery, D, Prunty, H, Brosnan, JT, Copp, AJ, Heales, S, Pai, YJ, Hutchin, T   +9 more
core  

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source