Results 21 to 30 of about 153,624 (265)

Impaired nutrient signaling and body weight control in a Na⁺ neutral amino acid cotransporter (Slc6a19)-deficient mouse [PDF]

open access: yes, 2015
Amino acid uptake in the intestine and kidney is mediated by a variety of amino acid transporters. To understand the role of epithelial neutral amino acid uptake in whole body homeostasis, we analyzed mice lacking the apical broad-spectrum neutral (0 ...
Bailey, Charles G.   +8 more
core   +1 more source

Genome-Wide Sequence Characterization and Expression Analysis of Major Intrinsic Proteins in Soybean (Glycine max L.)

open access: yesPLoS ONE, 2013
Water is essential for all living organisms. Aquaporin proteins are the major facilitator of water transport activity through cell membranes of plants including soybean.
D. Zhang   +11 more
semanticscholar   +1 more source

Phylogenetic and functional analysis of the Cation Diffusion Facilitator (CDF) family: improved signature and prediction of substrate specificity [PDF]

open access: yes, 2007
BACKGROUND The Cation Diffusion Facilitator (CDF) family is a ubiquitous family of heavy metal transporters. Much interest in this family has focused on implications for human health and bioremediation.
Blaudez, D.   +4 more
core   +3 more sources

Understanding the process of envelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses [PDF]

open access: yes, 2014
The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis.
Affranchino, Jose Luis   +1 more
core   +4 more sources

Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor

open access: yesBiomolecules, 2021
Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Raf Van Campenhout   +4 more
semanticscholar   +1 more source

Glycine, GABA and their transporters in pancreatic islets of Langerhans: evidence for a paracrine transmitter interplay

open access: yesJournal of Cell Science, 2004
To elucidate the possible roles of the CNS neurotransmitters glycine and GABA in neuroendocrine paracrine signalling, we investigated their localizations, and those of their transport proteins, by confocal immunofluorescence and quantitative post ...
Runhild Gammelsaeter   +7 more
semanticscholar   +1 more source

A Putative Plasma Membrane Na+/H+ Antiporter GmSOS1 Is Critical for Salt Stress Tolerance in Glycine max

open access: yesFrontiers in Plant Science, 2022
Soybean (Glycine max) is a staple crop and a major source of vegetable protein and vegetable oil. The growth of soybean is dramatically inhibited by salt stress, especially by the excessive toxic Na+.
Minghui Zhang   +11 more
semanticscholar   +1 more source

AtGAT1, a High Affinity Transporter for γ-Aminobutyric Acid in Arabidopsis thaliana*

open access: yesJournal of Biological Chemistry, 2006
Functional characterization of Arabidopsis thaliana GAT1 in heterologous expression systems, i.e. Saccharomyces cerevisiae and Xenopus laevis oocytes, revealed that AtGAT1 (At1g08230) codes for an H+-driven, high affinity γ-aminobutyric acid (GABA ...
Andreas J. Meyer   +3 more
semanticscholar   +1 more source

A guide to plasma membrane solute carrier proteins

open access: yesThe FEBS Journal, 2020
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily of transporter proteins and their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety ...
Mattia D. Pizzagalli   +2 more
semanticscholar   +1 more source

Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b

open access: yesEMBO Journal, 2021
Cholesterol is essential for cell physiology. Transport of the “accessible” pool of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) by ER‐localized GRAMD1 proteins (GRAMD1a/1b/1c) contributes to cholesterol homeostasis ...
Bilge Ercan   +4 more
semanticscholar   +1 more source

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