Results 61 to 70 of about 43,679 (304)
Diabetologia, 2022 Diabetic cardiomyopathy (DCM) is a serious and under-recognised complication of diabetes. The first sign is diastolic dysfunction, which progresses to heart failure.
Yan Qiu +15 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Endothelial dysfunction plays a central role in the pathogenesis of sepsis-mediated multiple organ failure. Several clinical and experimental studies have suggested that the glycocalyx is an early target of endothelial injury during an infection ...
Catherine Urban +7 more
semanticscholar +1 more source
A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx. [PDF]
PLoS ONE, 2010 BACKGROUND: Some low molecular weight heparins (LMWHs) prolong survival of cancer patients and inhibit experimental metastasis. The underlying mechanisms are still not clear but it has been suggested that LMWHs (at least in part) limit metastasis by ...
Geerte L Van Sluis +5 more
doaj +1 more source
Cells, 2022 Glycocalyx morphology was examined in the trabecular outflow pathway of monkey eyes with and without experimental glaucoma. Laser burns were administered along ~270 degrees of the trabecular meshwork (TM) of one eye (n = 6) or both eyes (n = 2) of each ...
Shayna Sosnowik +5 more
doaj +1 more source
Large-scale molecular dynamics simulation of coupled dynamics of flow and glycocalyx: towards understanding atomic events on an endothelial cell surface [PDF]
, 2017 The glycocalyx has a prominent role in orchestrating multiple biological processes occurring at the plasma membrane. In this paper, an all-atom flow/glycocalyx system is constructed with the bulk flow velocity in the physiologically relevant ranges for ...
Gong, H, Jiang, XZ, Luo, KH, Ventikos, Y
core +1 more source
Antifouling Glycocalyx-Mimetic Peptoids [PDF]
Journal of the American Chemical Society, 2013 The glycocalyx of the cell is composed of highly hydrated saccharidic groups conjugated to protein and lipid cores. Although components of the glycocalyx are important in cell-cell interactions and other specific biological recognition events, a fundamental role of the glycocalyx is the inhibition of nonspecific interactions at the cell surface ...
Ham, Hyun Ok +4 more
openaire +5 more sources
Cancers, 2022 Simple Summary The glycocalyx is a fluffy sugar coat covering the surface of all mammalian cells. While glycocalyx at endothelial cells is a barrier to tumor cell adhesion and transmigration, glycocalyx at tumor cells promotes tumor metastasis ...
Ye Zeng, Yan Qiu, Wenli Jiang, B. Fu
semanticscholar +1 more source
Multimodal measurement of glycocalyx degradation during coronary artery bypass grafting
Frontiers in Medicine, 2022 Background Glycocalyx shedding and subsequent endothelial dysfunction occur in many conditions, such as in sepsis, in critical illness, and during major surgery such as in coronary artery bypass grafting (CABG) where it has been shown to associate with ...
M. E. Bol +7 more
semanticscholar +1 more source
Understanding the basic role of glycocalyx during cancer
Journal of Radiation and Cancer Research, 2016 Metastasis or cancer is a functional, molecular and structural disorder which has been an unsolved and fatal mystery and leads to death in most of the individuals suffering from it in spite of the advances made in biomedical and oncological fields ...
Yogendrakumar Harivansh Lahir
doaj +1 more source
Annals of Intensive Care, 2020 The endothelial glycocalyx comprises a complex layer of membrane-bound proteoglycans, secreted glycosaminoglycans, glycoproteins, glycolipids and bound plasma proteins such as albumin and antithrombin associated with the endothelial surface.
C. Aldecoa +3 more
semanticscholar +1 more source