Results 271 to 280 of about 345,366 (342)

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang   +6 more
wiley   +1 more source

Insights Into Effects of Natural Bioactive Components on Inflammatory Diseases in Respiratory Tract

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The increasing prevalence of inflammatory diseases in the respiratory tract worldwide has raised concerns, and due to its high prevalence and poor prognosis, it remains a clinical focus and research hotspot. These inflammatory diseases include airway inflammation, asthma, bacterial antigens‐induced tonsil epithelial inflammation, chronic ...
Jincan Luo   +4 more
wiley   +1 more source

Phillygenin Improves the Focal Adhesion Kinase/Glycogen Synthase Kinase 3β/β‐Catenin Axis to Promote Mesenchymal Stem Cell Osteogenic Differentiation

open access: yesPhytotherapy Research, EarlyView.
Schematic diagram of Phillygenin improves the focal adhesion kinase/glycogen synthase kinase 3β/β‐catenin axis to promote mesenchymal stem cell osteogenic differentiation. ABSTRACT Forsythiae Fructus, a traditional herb known for its anti‐inflammatory and antioxidant properties, has demonstrated inconclusive effects on bone metabolism in prior studies.
Yuchao Yang   +12 more
wiley   +1 more source

Mitochondrial dynamics in autoimmune diseases

open access: yesRheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma   +5 more
wiley   +1 more source

An uncommon case of neonatal asphyxia associated with infantile-onset Pompe disease. [PDF]

open access: yesItal J Pediatr
Leo F   +8 more
europepmc   +1 more source

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