Results 241 to 250 of about 56,617 (329)

Danon Disease Diagnosed by Multimodal Imaging. [PDF]

open access: yesJACC Case Rep
Li X, Yang W, Zhang X, Xu H, Wang R.
europepmc   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Enhanced lysosomal glycogen breakdown is associated with liver tumorigenesis in glycogen storage disease type III. [PDF]

open access: yesJHEP Rep
Montalvo-Romeral V   +26 more
europepmc   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa   +8 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild   +3 more
wiley   +1 more source

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet   +6 more
wiley   +1 more source

RNA-Based Therapies for Inherited Metabolic Disorders. [PDF]

open access: yesJ Inherit Metab Dis
Vootukuri RS   +5 more
europepmc   +1 more source

Pediatric liver transplantation with cyclosporine and steroids [PDF]

open access: yes, 1984
Gartner, JC   +6 more
core  

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