Results 131 to 140 of about 13,856,572 (229)

Impaired Hepatic Glucose Metabolism Is Associated With Glucose Intolerance in Mice Carrying α2 Isoform Na,K‐ATPase Mutation

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim The Na,K‐ATPase is important for energy demanding cellular processes, including essential components of substrate metabolism and metabolic flexibility. Mice heterozygous for the hemiplegic migraine‐related mutation, G301R, of the Na,K‐ATPase α2 isoform (α2+/G301R) demonstrated altered metabolism in the heart.
Christian Staehr, Tue Duy Nguyen, Tina Myhre Pedersen, Mikkel Vendelbo, Hans Christian Beck, Mads Kjolby, Rajkumar Rajanathan, Elena V. Bouzinova, Niels Jessen, Per Bendix Jeppesen, Alexander V. Chibalin, Vladimir V. Matchkov   +11 more
wiley   +1 more source

Noninfectious endocarditis as a novel cardiac manifestation of glycogen storage disease type IV: a case report. [PDF]

Transl Pediatr
Kingdon T, Ganta S, Shayan K, Schuchardt EL, Gomez-Arostegui J, Vellore Govardhan S.   +5 more
europepmc   +1 more source

Continuous Intraperitoneal Insulin Infusion for People With Type 1 Diabetes: A Literature Review and International Position Statement

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8801-8811, October 2026.
ABSTRACT Achieving glucose targets without hypoglycaemia is the treatment goal in type 1 diabetes. Structured education, intensified insulin injection regimens, continuous glucose monitoring, automated insulin delivery, and ongoing support from a multidisciplinary team all support people with type 1 diabetes to achieve this goal. Despite these advances,
Nick Oliver, Bernhard Gehr, Rayhan Lal, Peter R. van Dijk, Eric Renard   +4 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, Volume 20, Issue 9, Page 2262-2279, September 2026.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Alglucosidase alfa treatment alleviates liver disease in a mouse model of glycogen storage disease type IV. [PDF]

Mol Genet Metab Rep, 2016
Yi H, Gao F, Austin S, Kishnani PS, Sun B.   +4 more
europepmc   +1 more source

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease of unknown cause, marked by excessive deposition of extracellular matrix (ECM) components such as collagen. This pathological accumulation results in progressive destruction of the lung architecture and ultimately leads to respiratory failure.
Yining Zhang, Ling Teng, Limin Gong, Yuandong Fu, Minyi Qian   +4 more
wiley   +1 more source

Variable clinical presentation of glycogen storage disease type IV: from severe hepatosplenomegaly to cardiac insufficiency. Some discrepancies in genetic and biochemical abnormalities. [PDF]

Arch Med Sci, 2018
Szymańska E, Szymańska S, Truszkowska G, Ciara E, Pronicki M, Shin YS, Podskarbi T, Kępka A, Śpiewak M, Płoski R, Bilińska ZT, Rokicki D.   +11 more
europepmc   +1 more source

SHIP1 Restrains Hypoxia/Reoxygenation‐Induced Cytokine Secretion in Mouse Bone Marrow–Derived Mast Cells

European Journal of Immunology, Volume 56, Issue 9, September 2026.
(A) BMMCs are substantially more resistant to oxygen deprivation than neurons, microglia, oligodendrocytes, astrocytes, and fibroblasts. (B) Role of SHIP‐1 in primary mouse bone marrow mast cells’ hypoxia response. Under hypoxia, SHIP‐1 induces cytokine release. SHIP1 restrains hypoxia/reoxygenation‐induced cytokine secretion in BMMCs via the RAS/ RAF,
Lara Gubeljak, Jonas Pes, Eren Arik, Aaron T. Fehr, Mara Schietinger, Thomas Wilhelm, Sandro Capellman, Michael Huber, Pardes Habib   +8 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, Volume 58, Issue 5, Page 1396-1412, September 2026.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Nursing care about child with glycogen storage disease I. type

, 2018
Present Situation: Research investigation deals with nursing care of the child with glycogen storage disease type I., as well as its diagnosis, nutritional management and complications.
ŠŤASTNÍKOVÁ, Hana
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