Results 271 to 280 of about 81,861 (342)
We report the structure of M. tuberculosis isoprenyl diphosphate synthase Rv2173 in three forms, including two with substrate (isoprenyl diphosphate and dimethylallyl diphosphate) occupying the allylic substrate site in different binding poses, with different numbers of metal ions bound.
James A. Titterington+6 more
wiley +1 more source
Stereoelectronic Effect of Protecting Groups on the Stability of Galactosyl Donor Intermediates. [PDF]
Kwok RW+3 more
europepmc +1 more source
Summary The leaf economics spectrum (LES) describes a suite of functional traits that consistently covary at large spatial and taxonomic scales. Despite its importance at these larger scales, few studies have examined the major drivers of intraspecific variation in the LES – phenotypic plasticity and standing genetic variation.
Robert W. Heckman+8 more
wiley +1 more source
Why Are 5-Thioglycopyranosyl Donors More Axially Selective than their Glycopyranosyl Counterparts? A Low and Variable Temperature NMR Spectroscopy and Computational Study. [PDF]
Ahiadorme D+3 more
europepmc +1 more source
Abstract In the filamentous cyanobacterium Anabaena sp. PCC 7120, heterocyst formation is triggered by changes in the C/N‐ratio and relies on transcriptional reprogramming. The transcription factor PacR is considered a global regulator of carbon assimilation under photoautotrophic conditions, influencing the carbon concentrating mechanism and ...
Elisa Werner+6 more
wiley +1 more source
Frosted DNA: β‐Galactosidase Control of Oligonucleotide Activity
β‐Galactosidase is expressed at low level in many native cells and strongly upregulated in senescent cells. In the present study, we use β‐galactosidase activity as internal trigger to control the hybridization of oligonucleotides–eventually selective in senescent cells. ABSTRACT We introduce a novel approach for the control of oligonucleotides through
Fabian Sinsel+3 more
wiley +1 more source
Modeling of the Carbohydrate Oxacarbenium Ionic Intermediates of Glycosylation Reactions with Explicit Account for Protective Group Effects. [PDF]
Gerbst AG+3 more
europepmc +1 more source
Biosynthesis of glycosyl phosphatidylinositol protein anchors
Tamara L. Doering+4 more
openalex +1 more source