Interferon-inducible guanylate-binding protein 5 inhibits replication of multiple viruses by binding to the oligosaccharyltransferase complex and inhibiting glycoprotein maturation. [PDF]
Wang S +13 more
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
A Survey of Opsin Localization, Glycosylation, and Light/Chromophore Influence on Degeneration in 26 Rhodopsin-Associated RP Models. [PDF]
Loewen AD +4 more
europepmc +1 more source
Development of Komagataella phaffii Cell‐Free Protein Synthesis Using Cell From Basic Salt Medium
This process illustrates a three‐step procedure for K. phaffii CFPS setup. First, K. phaffii cells are cultivated in basic salt medium and harvested by centrifugation. Then, cell extract is prepared from cell pellets through ultrasonic disruption, dialysis, centrifugation, and lyophilisation. Finally, K.
Yu Zhang +4 more
wiley +1 more source
Genome-wide characterization of the UDP-glycosyltransferases (UGT) family and functional analysis of VcUGT160 involved in dihydrozeatin glycosylation during blueberry fruits development. [PDF]
Wang Y +6 more
europepmc +1 more source
Multiple Strategies for Recombinant Expression of Human Chymotrypsinogen C in Pichia Pastoris
Human chymotrypsin C (CTRC), a food‐processing protease, was expressed in Pichia pastoris via three strategies: replacing the AOX1 promoter with HpHMD, rDNA locus‐based gene integration, and engineering the pro2M mutant to evade host protease degradation. The pro2M showed 3.3‐fold higher specific activity (54.84 U/mg) and improved secretion relative to
Yi Liu +5 more
wiley +1 more source
Glycolytic flux sustains human Th1 identity and effector function via STAT1 glycosylation. [PDF]
Abir AH +8 more
europepmc +1 more source
Development, Scope, and Catalyst Selection in Boron-Catalyzed Iterative Glycosylation. [PDF]
Harale KR +7 more
europepmc +1 more source
Iron-Catalyzed Highly Stereospecific Glycosylation with Glycal Epoxides. [PDF]
Zhang XW +5 more
europepmc +1 more source

