Results 161 to 170 of about 2,494,579 (210)

Glycyrrhizic acid: the assessment of a no effect level

Human & Experimental Toxicology, 2000
Because from earlier experiments in rats and a pilot study in humans a no effect level of glycyrrhizic acid could not be established, a second experiment was performed in healthy volunteers. The experiment was performed in females only, because the effects were most marked in females in the pilot study.
van Gelderen, CEM, Bijlsma, JA, van Dokkum, W, Savelkoul, TJF   +3 more
openaire   +4 more sources

Reduction of glycyrrhizic acid

Russian Chemical Bulletin, 1997
The reduction of glycyrrhizic acid by NaBH4 and LiAlH4 was studied. The conditions for the selective reduction of the COOH groups of the carbohydrate chain and the C(11)=0 group of aglycon were found.
L. A. Baltina, N. G. Serdyuk, E. V. Vasil’eva, G. A. Tolstikov   +3 more
openaire   +1 more source

Effect of Glycyrrhizic Acid on Lappaconitine Phototransformation

The Journal of Physical Chemistry B, 2007
1H NMR and CIDNP methods were used to demonstrate that triterpene glycoside (glycyrrhizic acid, GA) can substantially change the efficiency and direction of phototransformation of alkaloid lappaconitine (LA) due to both its solubilization in GA micelles and protonation of LA amine nitrogen in water-alcohol solutions.
Valeria S, Kornievskaya, Alexander I, Kruppa, Nicholas E, Polyakov, Tatyana V, Leshina   +3 more
openaire   +2 more sources

Some properties of glycyrrhizic acid

Chemistry of Natural Compounds, 1994
The chemical and spectral properties of crystalline specimens of glycyrrhizic acid and its monoammonium salt have been studied. On the basis of1H and13C NMR results, diagnostic parameters of the 18β/18α-epimers have been revealed, and features of the structure of the carbohydrate moiety of these compounds are discussed.
G. G. Zapesochnaya, E. N. Zvonkova, V. A. Kurkin, E. V. Kazakova, L. N. Pervykh, B. I. Sheichenko, V. A. Bykov   +6 more
openaire   +1 more source

Advances in Pharmacological Activities and Mechanisms of Glycyrrhizic Acid

Current Medicinal Chemistry, 2020
Licorice (Glycyrrhiza glabra L.) is widely regarded as an important medicinal plant and has been used for centuries in traditional medicine because of its therapeutic properties. Studies have shown that metabolites isolated from licorice have many pharmacological activities, such as antiinflammatory, anti-viral, participation in immune regulation ...
Kun Chen, Rong Yang, Fa-Qian Shen, Hai-Liang Zhu   +3 more
openaire   +2 more sources

Self-assembly in saponin mixtures: Escin/tea, tea/glycyrrhizic acid, and escin/glycyrrhizic acid mixtures

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021
Abstract Saponins are plant based biosurfactants that are obtained from a wide variety of plant species. They are surface active glycosides with a hydrophobic group, which is commonly a triterpenoid or steroidal group, and saccharide hydrophilic units.
I.M. Tucker, A. Burley, R.E. Petkova, S.L. Hosking, J.R.P. Webster, P.X. Li, K. Ma, J. Doutch, J. Penfold, R.K. Thomas   +9 more
openaire   +1 more source

Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone

American Journal of Physiology-Endocrinology and Metabolism, 1992
The apparent mineralocorticoid excess syndrome of patients ingesting large amounts of licorice or its derivatives is thought to be caused by the antagonism by these compounds of the enzyme 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD). 11 beta-HSD inactivates cortisol and corticosterone, allowing the more abundantly produced glucocorticoids access
E P, Gomez-Sanchez, C E, Gomez-Sanchez
openaire   +2 more sources

Research Progress of Glycyrrhizic Acid on Antiviral Activity

Mini-Reviews in Medicinal Chemistry, 2019
Glycyrrhizic acid (GA), a triterpene isolated from the roots and rhizomes of licorice, named Glycyrrhiza glabra, is the principal bioactive ingredient of anti-viral, anti-inflammatory and hepatoprotective effects. GA has been used in the clinical treatment of hepatitis, bronchitis, gastric ulcer, AIDS (acquired immunodeficiency syndrome), certain ...
Zhi-Gang, Sun, Ting-Ting, Zhao, Na, Lu, Yong-An, Yang, Hai-Liang, Zhu   +4 more
openaire   +2 more sources

Isolating and Purification Technologies for Glycyrrhizic Acid

Journal of Separation Science
ABSTRACT Glycyrrhizic acid (GA) is the primary active component of the traditional Chinese medicinal herb licorice. It possesses antimicrobial, anti‐inflammatory, and antitumor activities. In addition, due to its unique sweetness, it can also be used as a food additive.
Meng, Zhao, Qing, Wang, Yun, Yang, Lanlan, Sun, Xue-Song, Gu, Chang-Jiang-Sheng, Lai   +5 more
openaire   +2 more sources

New Amino-Acid Conjugates of Glycyrrhizic Acid

Chemistry of Natural Compounds, 2014
New conjugates of glycyrrhizic acid (GA) containing two amino-acid methyl esters (4-aminobutanoic, 6-aminohexanoic, 11-aminoundecanoic) were synthesized by the activated-ester method using N-hydroxysuccinimide (HOSu)-N,N′-dicyclohexylcarbodiimide (DCC).
L. A. Baltina, O. V. Stolyarova, L. A. Baltina, R. M. Kondratenko, V. A. Fedorova, Ya. A. Orshanskaya, V. V. Zarubaev   +6 more
openaire   +1 more source