Results 31 to 40 of about 16,670 (212)
PLoS ONE, 2021 During the glyoxylate cycle, isocitrate lyases (ICLs) catalyze the lysis of isocitrate to glyoxylate and succinate. Itaconate has been reported to inhibit an ICL from Mycobacterium tuberculosis (tbICL).
Sunghark Kwon +4 more
doaj +1 more source
Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis
Molecular Systems Biology, 2021 The co‐catabolism of multiple host‐derived carbon substrates is required by Mycobacterium tuberculosis (Mtb) to successfully sustain a tuberculosis infection. However, the metabolic plasticity of this pathogen and the complexity of the metabolic networks
Khushboo Borah +15 more
doaj +1 more source
Metabolic fitness of Candida albicans is indispensable for functional drug efflux, ergosterol, and chitin biosynthesis [PDF]
Current Medical Mycology, 2020 Background and Purpose: The increment in fungal infections, particularly due to Candida species, is alarming due to the emergence of multidrug resistance (MDR).
Sandeep Hans +2 more
doaj +1 more source
Two canonically aerobic foraminifera express distinct peroxisomal and mitochondrial metabolisms
Frontiers in Marine Science, 2022 Certain benthic foraminifera thrive in marine sediments with low or undetectable oxygen. Potential survival avenues used by these supposedly aerobic protists include fermentation and anaerobic respiration, although details on their adaptive mechanisms ...
Christopher Powers +11 more
doaj +1 more source
PLoS ONE, 2016 Mycobacterium tuberculosis can maintain a nonreplicating persistent state in the host for decades, but must maintain the ability to efficiently reactivate and produce active disease to survive and spread in a population.
Michelle M Giffin +3 more
doaj +1 more source
Aconitase: To Be or not to Be Inside Plant Glyoxysomes, That Is the Question
Biology, 2020 After the discovery in 1967 of plant glyoxysomes, aconitase, one the five enzymes involved in the glyoxylate cycle, was thought to be present in the organelles, and although this was found not to be the case around 25 years ago, it is still suggested in ...
Luigi De Bellis +2 more
doaj +1 more source
Frontiers in Microbiology, 2017 Growth on acetate or other acetyl-CoA-generating substrates as a sole source of carbon requires an anaplerotic pathway for the conversion of acetyl-CoA into cellular building blocks.
Farshad Borjian +5 more
doaj +1 more source
Microorganisms, 2022 Although the study of aerobic methane-oxidizing bacteria (MOB, methanotrophs) has been carried out for more than a hundred years, there are many uncultivated methanotrophic lineages whose metabolism is largely unknown.
Yuanfeng Cai, Juanli Yun, Zhongjun Jia
doaj +1 more source
Fat-to-glucose interconversion by hydrodynamic transfer of two glyoxylate cycle enzyme genes
Lipids in Health and Disease, 2008 The glyoxylate cycle, which is well characterized in higher plants and some microorganisms but not in vertebrates, is able to bypass the citric acid cycle to achieve fat-to-carbohydrate interconversion.
Marzo F +4 more
doaj +1 more source
Enzymes of the Glyoxylate Cycle in Rhizobia and Nodules of Legumes [PDF]
Plant Physiology, 1966 The relatively high level of fatty acids in soybean nodules and rhizobia from soybean nodules suggested that the glyoxylate cycle might have a role in nodule metabolism. Several species of rhizobia in pure culture were found to have malate synthetase activity when grown on a number of different carbon sources.
Temay Ching +2 more
openaire +2 more sources