Results 91 to 100 of about 9,808 (213)

Novel Water‐Soluble, Heavy Atom‐Free Thioxanthene‐Fused Naphthalimide–Polyamine Phototheranostic Conjugates

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Water‐soluble, heavy‐atom‐free naphthalimide–polyamine conjugates were developed as novel phototheranostic agents. Conjugates 2 and 3 showed effective photocytotoxicity in MCF‐7 cells with negligible dark toxicity. Fluorescence imaging confirmed efficient cellular uptake.
Elisa Uliassi, Michele Rossi, Matteo Di Giosia, Amalia Conti, Matteo Calvaresi, Kerry J. Rhoden, Maria Laura Bolognesi   +6 more
wiley   +1 more source

Supramolecular Host‐Guest Complexation Dynamics by Cost‐Efficient Electronic Structure Methods

Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.
We present a cost‐effective multilevel workflow for the kinetic profiling of host–guest systems, illustrated with cucurbit[6]uril and alkylammonium cations. The method combines rapid docking and reaction path searches at the semi‐empirical level, with refinement of the results using modern density functional theory, accurately reproducing experiment ...
Thomas Gasevic, Christoph Plett, Lukas Wittmann, Iago Neira, Carlos Peinador, Marcos D. García, Andreas Hansen   +6 more
wiley   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, Volume 13, Issue 45, 13 August 2026.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1773-1782, August 2026.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman, Carli M. Tops, Jelmer Legebeke, Ting Yang, Marcos Díaz Gay, Diantha Terlouw, Lisa E. E. L. O. Lashley, Stefan Aretz, Anna K. Sommer, Mariona Terradas, Laura Valle, Richarda M. de Voer, Ludmil B. Alexandrov, Hans Morreau, Tom van Wezel, Maartje Nielsen   +15 more
wiley   +1 more source

Temporalis muscle biomarkers from routine brain MRI and risk of dementia in two independent cohorts

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Skeletal muscle loss is associated with cognitive decline, but whether neuroimaging‐derived muscle characteristics predict incident dementia remains unclear. METHODS We evaluated associations of deep learning–derived temporalis muscle (TM) cross‐sectional area (CSA) and radiomic texture features from baseline T1‐weighted magnetic ...
Kamyar Moradi, Roham Hadidchi, Amyn Majbri, Timothy M. Hughes, Hanzhang Lu, Yuxin Zhu, Soheil Mohammadi, Sara Momtazmanesh, Pratik Mukherjee, Muhammad Abdullah, Eleanor Simonsick, Jennifer A. Schrack, Marcus D. Goncalves, Josef Coresh, Marilyn Albert, Shadpour Demehri   +15 more
wiley   +1 more source

Proteomic signatures of protected APOE ε4 carriers reveal causal pathways associated with delayed Alzheimer's disease onset

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION APOE ε4 is the strongest common genetic risk factor for Alzheimer's disease (AD), yet many carriers remain cognitively unimpaired into late life. We tested whether protected ε4‐first plasma proteomics could identify proteins associated with delayed clinical onset.
Yann Le Guen, Junyoung Park, Andrés Peña‐Tauber, Michael D. Greicius   +3 more
wiley   +1 more source

Improving Geomagnetic Perturbation Forecasts in the Southern Hemisphere via Kernel‐Based Encoding of Mirror Symmetry

Journal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 4, August 2026.
Abstract Accurate forecasting of geomagnetic perturbations is essential for assessing space weather risk of geomagnetic activities. Thanks to decades of magnetometer observations from world‐wide distributed networks and upstream solar wind observations at L1, data‐driven modeling of global geomagnetic perturbations has become increasingly feasible ...
Hongfan Chen, Gabor Toth, Yang Chen, Shasha Zou, Xun Huan   +4 more
wiley   +1 more source

GMDS Gene [PDF]

, 2020
openaire   +1 more source

Influence of Explicit Tropospheric VOC Chemistry on the Top‐Of‐Atmosphere Net Radiation Budget: Differences Between Two Preindustrial CESM2 Chemistry Configurations

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 14, 28 July 2026.
Abstract The representation of volatile organic compound (VOC) chemistry in earth system models directly impacts aerosol formation. Previous work shows explicitly representing VOC chemistry produces significant impacts on simulated climate compared to an implicit “SOAG scheme” that prescribes a bulk gas‐phase precursor to secondary organic aerosol (SOA)
Noah A. Stanton, Neil F. Tandon
wiley   +1 more source

Ganho de peso antes e após os sete meses no desenvolvimento e nas características de carcaça e carne de novilhos charolês abatidos aos dois anos

Revista Brasileira de Zootecnia, 2003
Foram estudados o desenvolvimento e as características de carcaça de 157 novilhos Charolês abatidos aos dois anos de idade, classificados em quatro grupos, conforme o ganho de peso médio diário (GMD) antes e após os sete meses: "alto-alto" = novilhos com
Fabiano Nunes Vaz, João Restle
doaj