Results 51 to 60 of about 121,331 (374)

Groundwater flow modeling and hydraulic assessment of Al-Ruhbah region, Iraq

Journal of the Mechanical Behavior of Materials, 2023
Al-Ruhbah region is located in the southwest of Najaf Governorate. A numerical model was created to simulate groundwater flow and analyze the water quality of the groundwater, by developing a conceptual model within the groundwater modeling system ...
Zwain Hanadi H., Abed Basim Sh.
doaj   +1 more source

Re-evaluating green marketing strategy : a stakeholder perspective [PDF]

, 2007
Purpose The present study aims to examine the influence of stakeholders on green marketing strategy (GMS). Marketing literature recognizes that stakeholders play a significant role in influencing organizations and markets, but has not targeted a single
Rivera Camino, Jaime
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Influence of underground space development mode on the groundwater flow field in Xiong’an new area

Journal of Groundwater Science and Engineering, 2023
The degree and scale of underground space development are growing with the continuous advancement of urbanization in China. The lack of research on the change of the groundwater flow field before and after the development of underground space has led to ...
Yi-hang Gao, Jun-hui Shen, Lin Chen, Xiao Li, Shuang Jin, Zhen Ma, Qing-hua Meng   +6 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Application of MODFLOW and MT3DMS Models to Evaluate Groundwater Quantity and Quality in Northern Iran [PDF]

Journal of Hydraulic and Water Engineering
In recent decades, climate change and drought have led to an increase in groundwater use in the world. In Iran, due to being in the global dry belt and also the impact of climate change, reduced rainfall and surface water, excessive use of groundwater ...
Atikeh Afzali, Kaka Shahedi
doaj   +1 more source

Gradient Magnitude Similarity Deviation: A Highly Efficient Perceptual Image Quality Index [PDF]

IEEE Transactions on Image Processing, 2013
It is an important task to faithfully evaluate the perceptual quality of output images in many applications, such as image compression, image restoration, and multimedia streaming.
Wufeng Xue, Lei Zhang, X. Mou, A. Bovik
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

تغییرات کمی منابع آب زیرزمینی دشت میاندوآب تحت تأثیر سیاست‌های انقباضی تخصیص آب [PDF]

پژوهش‌های حفاظت آب و خاک
سابقه و هدف: به علت محدودیت‌های منابع تجدیدشونده آب شیرین، مدیریت صحیح میان منابع و مصارف، یکی از عوامل اصلی برای دستیابی به مدیریت پایدار است . هدف در این پژوهش بررسی تأثیرات سیاست انقباضی دولت در قبال کاهش حق آبه سطحی و زیرزمینی در دشت میاندوآب و بررسی
احسان جوادی, بهزاد حصاری, مهسا محمد حسین زاده   +2 more
doaj   +1 more source