Results 41 to 50 of about 1,063 (133)

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Cryptic diversity and recent diversification in the Pyrrhulina australis species complex (Characiformes, Lebiasinidae) revealed by mitochondrial DNA

Journal of Fish Biology, EarlyView.
Abstract Pyrrhulina australis Eigenmann & Kennedy, 1903, is widely distributed across the main hydrographic basins of South America. The taxonomic integrity of this species is nevertheless challenged by the lack of clear diagnostic characters, its marked geographic variation and the morphological overlap with its congeners. In this context, the present
Taina Barbosa De Souza, Daniela Cristina Ferreira, Hugmar Pains Da Silva, Carolina B. Machado, Claudio Oliveira, André L. Netto‐Ferreira, Paulo C. Venere   +6 more
wiley   +1 more source

Filter feeders living on suspension feeders: New insights into the lifestyle and distribution of Arcturidae Dana, 1849 (Crustacea: Isopoda) around Iceland

Marine Ecology, EarlyView.
Abstract The focus of the present study was on arcturid isopods occurring in the subarctic region around Iceland. Data from two decades of sampling with an epibenthic sledge (EBS) during numerous expeditions of the BIOICE (Benthic Invertebrates of Icelandic Waters; 1992–2004) and IceAGE (Icelandic marine Animals: Genetics and Ecology; 2011—ongoing ...
Vivien Lukas Hartmann, Emanuel Pereira, Nancy F. Mercado‐Salas, Anne‐Nina Lörz, Jörundur Svavarsson, Saskia Brix   +5 more
wiley   +1 more source

Reconciling morphological and molecular approaches: The integrative taxonomy of Leucobryum (Leucobryaceae) in the Malagasy region

TAXON, Volume 75, Issue 4, August 2026.
Abstract Leucobryum (Leucobryaceae) is a genus of moss (Bryophyta) that has been poorly investigated in Africa, particularly in the western Indian Ocean region. This study integrates morphological and molecular data to revise the taxonomy of the genus in this area.
Quentin Dejonghe, Roger Lala Andriamiarisoa, Claudine Ah‐Peng, Roland Marmeisse, Catherine Reeb   +4 more
wiley   +1 more source

A revision of the genus Armeria (Plumbaginaceae) in peninsular Italy and Sicily through an integrative taxonomic approach

TAXON, Volume 75, Issue 4, August 2026.
Abstract The genus Armeria in peninsular Italy has been affected by taxonomic ambiguity for more than a century due to high morphological variability. We present a comprehensive revision of peninsular Italian and Sicilian Armeria species, using an integrated taxonomic approach that combines molecular phylogeny, plant and seed morphometrics, and ...
Manuel Tiburtini, Gianluigi Bacchetta, Fabrizio Bartolucci, Liliana Bernardo, Fabio Conti, Emanuela Di Iorio, Gianniantonio Domina, Duilio Iamonico, Mauro Iberite, Luca Paino, Marco Sarigu, Paolo Caputo, Lorenzo Peruzzi   +12 more
wiley   +1 more source

Clarifying the Labrisomus Conundrum: Deep Divergence, Cryptic Lineages, and a Genetic Melting Pot in the Atlantic Ocean (Teleostei, Labrisomidae)

Journal of Biogeography, Volume 53, Issue 8, August 2026.
ABSTRACT Aim We evaluate the phylogenetic relationships and taxonomic validity of Atlantic species of Labrisomus, identifying the lineages currently assigned to L. nuchipinnis, and assessing the role of biogeographic barriers in shaping the evolutionary history and geographic distribution of the genus. Location Atlantic Ocean.
Gabriel Soares Araujo, João Luiz Gasparini, Luiz A. Rocha, Hudson T. Pinheiro, Marcelo V. Kitahara, Anderson V. Vilasboa, Carol A. Stepien, Sergio R. Floeter, Fabio Di Dario   +8 more
wiley   +1 more source

Phylogenetic species delimitation for crayfishes of the genus Pacifastacus [PDF]

PeerJ, 2016
Molecular genetic approaches are playing an increasing role in conservation science by identifying biodiversity that may not be evident by morphology-based taxonomy and systematics.
Eric R. Larson, Magalie Castelin, Bronwyn W. Williams, Julian D. Olden, Cathryn L. Abbott   +4 more
doaj   +2 more sources

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, Volume 13, Issue 40, 17 July 2026.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

DNA barcoding for community ecology--how to tackle a hyperdiverse, mostly undescribed Melanesian fauna. [PDF]

PLoS ONE, 2012
BACKGROUND: Trigonopterus weevils are widely distributed throughout Melanesia and hyperdiverse in New Guinea. They are a dominant feature in natural forests, with narrow altitudinal zonation.
Rene Tänzler, Katayo Sagata, Suriani Surbakti, Michael Balke, Alexander Riedel   +4 more
doaj   +1 more source

Integrative Taxonomy of Pachygrontha (Heteroptera: Pachygronthidae) in East and Southeast Asia Reveals New Insights Into Species and Group Delimitation

Ecology and Evolution, Volume 16, Issue 7, July 2026.
This manuscript presents a comprehensive taxonomic revision of the insect genus Pachygrontha in East and Southeast Asia, addressing the critical need for robust species delimitation in closely related lineages. Our research employs an integrative approach, combining detailed morphological examination with complete mitochondrial genomes and genome‐wide ...
Kaibin Wang, Cuiqing Gao, Ying Wang, Siying Fu, Wenjun Bu   +4 more
wiley   +1 more source