Results 311 to 320 of about 7,213,451 (363)

Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial. [PDF]

PLOS Glob Public Health
Ouyang M, Anjum A, Mc Cawley FG, Wasay M, Ma L, Hu X, Chen X, Malavera A, Li X, Venturelli PM, Silva HA, Thang NH, Wahab KW, Pandian JD, Pontes-Neto OM, Abanto C, Cano-Nigenda V, Arauz A, You C, Jan S, Song L, Anderson CS, Liu H, INTERACT3 Investigators.   +23 more
europepmc   +1 more source

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

Advanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Elia A. Guzzi, Lorenza Garau Paganella, Luca Liebi, Julien Draussin, Pedro Lopez Navarro, Elsa Barbé, Olivier Lefebvre, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Sébastien Harlepp, Mark W. Tibbitt, Alexandre Detappe   +17 more
wiley   +1 more source

Intraoperative goal-directed fluid therapy in neurosurgical patients: A systematic review. [PDF]

Surg Neurol Int
Kutum C, Lakhe P, Ghimire N, Bc AK, Begum U, Singh K.   +5 more
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Intraoperative goal-directed fluid management and postoperative brain edema in patients having high-grade gliomas resections: a randomized trial. [PDF]

Int J Surg
Liu X, Zhang X, Fan Y, Wang B, Wang J, Zeng M, Li S, Shen M, Zhang W, Sessler DI, Peng Y.   +10 more
europepmc   +1 more source

Implementing BMP‐7 Chemically Modified RNA for Bone Regeneration with 3D Printable Hyaluronic Acid‐Collagen Granular Gels

Advanced Healthcare Materials, EarlyView.
This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide, Claudia del Toro Runzer, Elena Della Bella, Christian Plank, Martijn van Griensven, Elizabeth Rosado Balmayor, Martin J. Stoddart, Matteo D'Este   +7 more
wiley   +1 more source

Goal-directed osteoporosis treatment: ASBMR/BHOF task force position statement 2024. [PDF]

J Bone Miner Res
Cosman F, Lewiecki EM, Eastell R, Ebeling PR, Jan De Beur S, Langdahl B, Rhee Y, Fuleihan GE, Kiel DP, Schousboe JT, Borges JL, Cheung AM, Diez-Perez A, Hadji P, Tanaka S, Thomasius F, Xia W, Cummings SR.   +17 more
europepmc   +1 more source

Neurocomputational model of compulsivity: deviating from an uncertain goal-directed system. [PDF]

Brain
Kim T, Lee SW, Lho SK, Moon SY, Kim M, Kwon JS.   +5 more
europepmc   +1 more source

The effect of intraoperative goal-directed fluid therapy in patients under anesthesia for gastrointestinal surgery. [PDF]

World J Gastrointest Surg
Zhang J, Li XW, Xie BF.
europepmc   +1 more source

Systematic review and meta-analysis of goal-directed haemodynamic therapy algorithms during surgery for the prevention of surgical site infection. [PDF]

EClinicalMedicine
Jalalzadeh H, Hulskes RH, Weenink RP, Wolfhagen N, van Dusseldorp I, Schaad RR, Veelo DP, Hollmann MW, Boermeester MA, de Jonge SW.   +9 more
europepmc   +1 more source