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Early goal-directed therapy versus “early”, “goal-directed” therapy

Intensive Care Medicine, 2015
Dear Editor, I read with great interest the systematic review and meta-analysis by the ARISE, ProCESS and ProMISe investigators [1] that showed no difference in mortality between early goal-directed therapy (EGDT) and usual care in resuscitating patients with septic shock. I admire their work and this is a great opportunity to speak directly with them.
openaire   +3 more sources

Does goal-directed haemodynamic and fluid therapy improve peri-operative outcomes?: A systematic review and meta-analysis

European Journal of Anaesthesiology, 2018
BACKGROUND Much uncertainty exists as to whether peri-operative goal-directed therapy is of benefit. OBJECTIVES To discover if peri-operative goal-directed therapy decreases mortality and morbidity in adult surgical patients. DESIGN An updated systematic
Matthew A Chong   +3 more
semanticscholar   +1 more source

Early goal-directed therapy in the treatment of severe sepsis and septic shock.

New England Journal of Medicine, 2018
BACKGROUND Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen delivery with oxygen demand.
E. Rivers   +7 more
semanticscholar   +1 more source

Goal Directed Fluid Therapy

Current Pharmaceutical Design, 2012
The cornerstone of treating patients with shock remains as it has for decades, intravenous fluids. Surprisingly, dosing intravenous fluid during resuscitation of shock remains largely empirical. Recent data suggests that early aggressive resuscitation of critically ill patients may limit and/or reverse tissue hypoxia, progression to organ failure and ...
Himanshu Desai, Paul E. Marik
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Goal Directed Dynamics

2018 IEEE International Conference on Robotics and Automation (ICRA), 2018
We develop a general control framework where a low-level optimizer is built into the robot dynamics. This optimizer together with the robot constitute a goal directed dynamical system, controlled on a higher level. The high level command is a cost function. It can encode desired accelerations, end-effector poses, center of pressure, and other intuitive
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Imaging Goal-Directed Movement

Research Quarterly for Exercise and Sport, 1995
The main purpose of the present investigation was to determine how Shepard's (1968) second-order isomorphic principle relates to imaging goal-directed movement. Reports of movement times for actual and imaged movements were obtained using Fitts-type tapping tasks.
Sebastiano A. Fisicaro, Robert M. Kohl
openaire   +3 more sources

Goal-directed treatment of osteoporosis in Europe

Osteoporosis International, 2014
Despite the proven predictive ability of bone mineral density, Fracture Risk Assessment Tool (FRAX®), bone turnover markers, and fracture for osteoporotic fracture, their use as targets for treatment of osteoporosis is limited.Treat-to-target is a strategy applied in several fields of medicine and has recently become an area of interest in the ...
J. A. Kanis   +10 more
openaire   +8 more sources

Newborns’ preference for goal-directed actions

Cognition, 2011
The central role of sensory-motor representations in cognitive functions is almost universally accepted. However, determining the link between motor execution and its sensory counterpart and when, during ontogenesis, this link originates are still under investigation.
CRAIGHERO L   +3 more
openaire   +5 more sources

Goal-Directed Actions

2017
Personal causation relies on translating goals into goal-directed behavior. This chapter addresses how humans generate a goal-directed behavior, that is, how they initiate and control intentional, goal-directed actions. In particular, it discusses how anticipated action effects are integrated with motor patterns, so to guide future effect-driven ...
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Goal-Directed Program Transformation

IEEE Transactions on Software Engineering, 1976
Program development often proceeds by transforming simple, clear programs into complex, involuted, but more efficient ones. This paper examines ways this process can be rendered more systematic. We show how analysis of program performance, partial evaluation of functions, and abstraction of recursive function definitions from recurring subgoals can be ...
openaire   +3 more sources

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