Results 41 to 50 of about 297,292 (254)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Feature-Based Face Detection: A Survey [PDF]

Iraqi Journal for Computers and Informatics, 2018
Human and computer vision has a vital role in intelligent interaction with computer, face recognition is one of the subjects that have a wide area in researches, a big effort has been exerted in last decades for face recognition, face detection, face ...
Abbas M. Albakri, Safaa O. Almamory, Hadeel H. Alfartosy   +2 more
doaj   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

BOARD-AI: A goal-aware modeling interface for systems engineering, combining machine learning and plan recognition

Frontiers in Physics, 2022
Paper and pens remain the most commonly used tools by systems engineers to capture system models. They improve productivity and foster collaboration and creativity as the users do not need to conform to formal notations commonly present in Computer-Aided
Sandra Castellanos-Paez, Nicolas Hili, Alexandre Albore, Mar Pérez-Sanagustín   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Reverse Thinking Approach to Deceptive Path Planning Problems

Mathematics
Deceptive path planning (DPP) aims to find routes that reduce the chances of observers discovering the real goal before its attainment, which is essential for addressing public safety, strategic path planning, and preserving the confidentiality of ...
Dejun Chen, Quanjun Yin, Kai Xu
doaj   +1 more source

A Decentralized Partially Observable Markov Decision Model with Action Duration for Goal Recognition in Real Time Strategy Games

Discrete Dynamics in Nature and Society, 2017
Multiagent goal recognition is a tough yet important problem in many real time strategy games or simulation systems. Traditional modeling methods either are in great demand of detailed agents’ domain knowledge and training dataset for policy estimation ...
Peng Jiao, Kai Xu, Shiguang Yue, Xiangyu Wei, Lin Sun   +4 more
doaj   +1 more source

Stochastic Goal Recognition Design

Proceedings of the AAAI Conference on Artificial Intelligence, 2019
Given an environment and a set of allowed modifications, the task of goal recognition design (GRD) is to select a valid set of modifications that minimizes the maximal number of steps an agent can take before its goal is revealed to an observer. This document presents an extension of GRD to the stochastic domain: the Stochastic Goal Recognition Design (
openaire   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source