Results 231 to 240 of about 1,082,443 (303)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Rapid Generation of Transition-State Conformer Ensembles via Constrained Distance Geometry. [PDF]

J Chem Inf Model
Schmid SP, Seng H, Kläy T, Jorner K.
europepmc   +1 more source

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

Advanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao, Chao Ren, Li‐Yu Zheng, Jing‐Yan Li, Wen‐Feng Wu, Yu‐Xuan Li, Li‐Xue Wang, Yu Duan, Lu Wang, Shuang‐Qing Liu, Peng‐Yi He, Peng‐Yue Zhao, Sen Tong, Zhi‐Xuan Li, Tuo Zhang, Meng‐Yao Wu, Shu‐Ting Wei, Ning Dong, Yao Wu, Hui Zhang, Xiao‐Mei Zhu, Zi‐Cheng Zhang, Guo‐Sheng Wu, Zhao‐Fan Xia, Xiao‐Hui Du, Hong‐Jun Kang, Zui Zou, Dao‐Lin Tang, Yong‐Ming Yao   +28 more
wiley   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Serological Insights into Infectious Agents Circulating in Lithuanian Goats. [PDF]

Vet Sci
Klibavičė P, Kupčinskas T, Petkevičius S, Buitkuvienė J, Šalomskas A.   +4 more
europepmc   +1 more source

Development of a Vertical Flow Dot-Immunobinding Assay (Dot-Iba) for Rapid Detection of Neoscytalidium dimidiatum. [PDF]

Mycopathologia
Plengpanich A, Bunyaratavej S, Tungtrongchitr A, Saelim N, Srisai T, Leeyaphan C, Chongtrakool P, Ruenchit P.   +7 more
europepmc   +1 more source

Feasibility of low-field magnetic resonance imaging (lf-MRI) for longitudinally evaluating experimentally induced lumbar intervertebral disc injuries in goat models (Capra hircus): A pilot study. [PDF]

PLoS One
Jones JC, Krussig MJ, Breed MW, Harrison CD, Gilpin JW, Rimoldi GM, Mercuri JJ, Ali AAB, Bridges WC.   +8 more
europepmc   +1 more source

Mechanisms of impaired glucose transport in cryptosporidiosis in goat kids. [PDF]

BMC Vet Res
Krasilnikova V, Kuzmina E, Philippova A.
europepmc   +1 more source