Results 101 to 110 of about 10,905,136 (285)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats

Open Veterinary Journal
Background: Infectious diseases such as Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis have considerable impacts on the optimal utilization of sheep and goat resources in Ethiopia.
Takele Tesgera Hurisa, Takele Abayneh Tefera, Retta Negatu, Teshale Sori, Berecha Bayisa Deme, Mirtneh Akalu Yilma, Wondwossen Tolossa, Abinet Legesse, Ashetu Negewo, Wubet W/Medhin, Kedir Sherefa, Getu Ayele, Adugna Geresu, Eyob Assefa, Dawit Dufera   +14 more
doaj   +1 more source

Abscess diseases in goats

Macedonian veterinary review, 2015
Common name abscess diseases is used to describe two etiologically distinct diseases ; Morel disease caused by Staphylococcus aureus subsp. anaerobius and caseous lymphadenitis (CLA) caused by Corynebacterium pseudotuberculosis. Both diseases have similar epizootiology and are characterized by abscess formations in or near major superficial lymph nodes.
Turk, Nenad, Matanović, Krešimir, Šeol, Branka, Starešina, Vilim, Habuš, Josipa, Štritof, Zrinka, Milas, Zoran   +6 more
openaire   +1 more source

Chemical Maturation Controls Bioavailability of Fetuin‐A‐Mineral Complexes in Biomineralization

Advanced Functional Materials, EarlyView.
The role of Fetuin‐A‐mineral complexes in matrix mineralization is unclear. Here, Fetuin‐A‐mineral complexes were found to exist in functionally distinct states that determine mineral bioavailability: chemically labile calciprotein monomers directly mineralize collagen fibrils, while chemically matured primary calciprotein particles require cellular ...
Judith M. Schaart, Luco Rutten, Shaina V. To, Alisha A. Shah, Martijn Martens, Elena Macías‐Sánchez, Willi Jahnen‐Dechent, Nico Sommerdijk, Anat Akiva   +8 more
wiley   +1 more source

Glucose Deprivation‐Driven Concurrent Induction of Apoptosis/Disulfidptosis/Ferroptosis by Tumor Targeting Nanoassemblies in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Innovative hybrid nanoassemblies installed with ferrocene, D‐α‐tocopherol succinate, and phloretin exploit the metabolic vulnerability of triple‐negative breast cancer under glucose starvation. By blocking glucose uptake, this single nanoplatform simultaneously orchestrates apoptosis, disulfidptosis, and ferroptosis to achieve synergistic and ...
Song Yi Lee, ChaeRim Hwang, Seong Eun Kim, Mrinmoy Karmakar, Seo Jin Jung, Hyeonseok Jang, Hae‐In Kim, Heejung Yang, Junmin Lee, Dae‐Duk Kim, Hyun‐Jong Cho   +10 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Identification and Full-Length Sequence Analysis of a Novel Recombinant Goat Astrovirus Genotype in Guangxi, China

Viruses
Astroviruses are single-stranded, positive-sense RNA viruses capable of infecting humans as well as a wide range of mammalian and avian species, with a length of approximately 6.6–7.7 kb.
Yulu Zhou, Pengju Xu, Yanhua Huang, Jie Wang, Chang Cui, Yanglin Wang, Yuhang Luo, Xiaoling Wang, Jiang Xie, Fengmei Li, Zuzhang Wei, Ying Chen, Kang Ouyang, Yifeng Qin, Yan Pan, Weijian Huang   +15 more
doaj   +1 more source

The Production of Goat Milk under Organic Requests

Scientific Papers Animal Science and Biotechnologies, 2023
Organic farming has turned into a very important subject who consists in a food production label and it has become very popular. That is because, especially in the EU the majority of the dairy goat farms want or have already applied the organic farming ...
Roger Stan, Ramona Iancu, Alina Toader, Luiza Monafu, Mădălina Bobeică   +4 more
doaj