Results 191 to 200 of about 314,364 (262)

Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice

Advanced Science, EarlyView.
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang, Zhengting Chen, Pengxiang Bai, Biao Liu, Lingling Meng, Jian Zhang, Xu Li, Dao‐Xiu Zhou, Xuan Ma, Yu Zhao   +9 more
wiley   +1 more source

Molecular evidence of Echinococcus canadensis (G6/G7) predominance in Mongolian livestock and its implications for control. [PDF]

PLoS Negl Trop Dis
Bold B, Andrus PS, Bayasgalan C, Nergui D, Badmaa B, Cao Y, Su X, Mo X, Guugandaa N, Xiao N, Zhang T, Zhou XN.   +11 more
europepmc   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

Profiling cell dynamic changes of goat peripheral blood mononuclear cells after Pasteurella multocida infection with single-cell transcriptomics and histopathology. [PDF]

Vet Res
An Q, Chen T, Jiang J, Wu H, Wu G, Jiao Z, Li S, Meng Y, Tang J, Chen Y, Pan H, Li H, Zhang Z, Cheng Y, Fu Y, Huang Z, Manchu R, Chen Q, Wang F.   +18 more
europepmc   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Response to the Letter to the Editor Entitled "Defining "Dominance" in Atypical Hemolytic Uremic Syndrome: Distinguishing Amplification From Initiation". [PDF]

Kidney Int Rep
Aiello S, Santarsiero D, Gastoldi S, Benigni A, Remuzzi G, Noris M.   +5 more
europepmc   +1 more source

Tactile Preferences in Goats: Implications for Animal-Assisted Interventions. [PDF]

Animals (Basel)
Masier PM, Ziemiańska A, Janicka K, Janicka W, Wójcik M, Rozempolska-Rucińska I.   +5 more
europepmc   +1 more source

SQSTM1/p62 UFMylation Enhances Autophagic Clearance of Pathogenic Mutant Huntingtin. [PDF]

Int J Biol Sci
Wang X, Lv X, Jiang H, Zhu W, Cao L, Zhou L, Lin F, Deng R, Hu LF, Ma J, Li JB, Xu G.   +11 more
europepmc   +1 more source

Periparturient changes in oxidative stress and metabolic parameters in higher-parity Saanen goats with and without kid mortality at birth. [PDF]

Trop Anim Health Prod
Kutlu M, Durmuş M.
europepmc   +1 more source

Silent Propagation of Classical Scrapie Prions in Homozygous K₂₂₂ Transgenic Mice. [PDF]

Emerg Infect Dis
Fernández-Borges N, Marín-Moreno A, Espinosa JC, Canoyra S, Andréoletti O, Torres JM.   +5 more
europepmc   +1 more source