Results 11 to 20 of about 42,423 (208)

Refining OVCAR-3 xenograft models of peritoneal carcinomatosis in nu/nu mice: Comparative intraperitoneal implantation strategies and the role of basement membrane matrix. [PDF]

Animal Model Exp Med
A refined murine model of advanced ovarian cancer was established by comparing localized preperitoneal implantation and intraperitoneal injection of OVCAR‐3Luc cells. While localized implantation showed limited tumor persistence, intraperitoneal delivery with BME produced sustained diffuse dissemination confirmed by BLI and histology, providing a ...
Perelló-Trias MT, Serrano-Muñoz AJ, Segura-Sampedro JJ, Quintero-Duarte AM, Ramis JM, Monjo M.   +5 more
europepmc   +2 more sources

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Hydrophobic MFI‐Type Zeolites via Alkali‐Cation‐Induced Defect Healing: Implications for Adsorbent and Catalyst Design

Advanced Materials, EarlyView.
Sub‐stoichiometric amounts of Na+ or K+ enhance defect healing during Silicalite‐1 (MFI) and TS‐1 calcination by promoting Si–O–Si annealing and healing framework vacancies. The resulting defect‐free zeolites are more hydrophobic and show improved butanol/water separation and improved activity and selectivity in the epoxidation of 1‐hexene, offering a ...
Christos Kanteler, Pau Ferri, Francisco Javier Escobar‐Bedia, Álvaro Mayoral, Alejandro Vidal‐Moya, Richard Kendra, Chen Lei, Miguel Palomino, Fernando Rey, Lukáš Grajciar, Christopher James Heard, Pedro Serna, Mercedes Boronat, Cristina Martínez, Manuel Moliner   +14 more
wiley   +1 more source

Microenvironmental Tuning in Isostructural Conjugated Metal–Organic Frameworks for Superior Photocatalytic H2O2 Generation

Angewandte Chemie, EarlyView.
Two isostructural conjugated‐MOFs (Fe‐Tp and Mn‐Tp) photocatalysts were engineered with nonequivalent microenvironmental redox tuning for hydrogen peroxide production. The manganese analog engages both the oxygen reduction reaction and the water oxidation reaction while suppressing decomposition, delivering 10 487 µmol g−1 h−1 with an apparent quantum ...
Kayaramkodath Chandran Ranjeesh, Avanti Chakraborty, Pilar Pena Sánchez, Jose Ignacio Martinez, Abdul Khayum Mohammed, Nada Elmerhi, Stefano Canossa, Matjaž Finšgar, Felipe Gándara, Pradip Pachfule, Dinesh Shetty   +10 more
wiley   +2 more sources

Moonlighting of Haemophilus influenzae heme acquisition systems contributes to the host airway-pathogen interplay in a coordinated manner

Virulence, 2019
Nutrient iron sequestration is the most significant form of nutritional immunity and causes bacterial pathogens to evolve strategies of host iron scavenging.
Irene Rodríguez-Arce, Tamim Al-Jubair, Begoña Euba, Ariadna Fernández-Calvet, Celia Gil-Campillo, Sara Martí, Susanna Törnroth-Horsefield, Kristian Riesbeck, Junkal Garmendia   +8 more
doaj   +1 more source

Volatile Memristive Devices With Tunable Temporal Dynamics For Event‐Based Sensing

Advanced Materials, EarlyView.
Tunable volatile memristive devices can serve various neural‐inspired tasks that require different time windows of information retention. The ionic‐based volatility of the presented Pt/a‐STO/TaOx/Ta device stack can be reproducibly and controllably tuned in multiple ways.
Dimitrios Spithouris, Johannes Hellwig, Hugh Greatorex, Clemens Wittberg, Panagiotis Koutsogiannis, César Magén, Elisabetta Chicca, Regina Dittmann   +7 more
wiley   +1 more source

A Mechanical sp2‐Jail for C60 Fullerene

Angewandte Chemie, EarlyView.
A rigid bisporphyrin receptor with an exceptionally compact 3D cavity functions as a molecular “mechanical jail”, tightly enclosing C60 fullerene. Near‐perfect shape complementarity affords ultrahigh binding affinity while imposing a large kinetic barrier for guest exchange, rendering encapsulation effectively irreversible under ambient conditions ...
A. Priscila Gia, Fernando G. Guijarro, Pau Armada, Daniel Aranda, Josefina Perles, Enrique Ortí, Juan Aragó, David González‐Rodríguez, Alberto de Juan   +8 more
wiley   +2 more sources

Legionelosis esporádica: un problema sin resolver

Revista de Salud Ambiental, 2013
Objetivo: Resumir los hallazgos más relevantes obtenidos en diferentes estudios dirigidos a investigar el origen de la legionelosis esporádica. Métodos: Se ha realizado una búsqueda bibliográfica en revistas nacionales e internacionales (1990-junio ...
Ana Maria Jiménez Zabala, Loreto Santa Marina Rodriguez, Mónica Otazua Font, Yolanda Cuetos, Mikel Etxeberria Agirresarobe, Koldo de la Fuente Campos   +5 more
doaj   +2 more sources

Elasticity‐Driven Periodic Polarization Patterns in a Chiral Ferroelectric Nematic Fluid

Advanced Materials, EarlyView.
Chiral polar ferroelectric nematic fluids exhibit spontaneous formation of stripe, square, and hexagonal polarization textures under confinement. Controlled by thickness and anchoring, these patterns produce spatially modulated nonlinear optical responses.
Anej Sterle, Peter Medle Rupnik, Luka Cmok, Aitor Erkoreka, Marta Lavrič, Natan Osterman, Calum J. Gibb, Jordan Hobbs, Josu Martinez‐Perdiguero, Richard J. Mandle, Alenka Mertelj, Nerea Sebastián   +11 more
wiley   +1 more source