Results 251 to 260 of about 550,878 (300)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

Exploring drivers and costs of partial trans‐Saharan migration in juvenile vultures

open access: yesIbis, EarlyView.
Partial migration occurs when only a subset of individuals within a population undertakes a migratory journey. The decision to migrate can be influenced by intrinsic traits (e.g. sex or physical condition) as well as by extrinsic factors (e.g. social environment or resource availability).
Eneko Arrondo   +18 more
wiley   +1 more source

An efficient variable neighborhood search approach for the facility location problem with the limited choice rule

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract One of the most common problems in the expansion of a company consists of deciding the most appropriate locations for their facilities. This decision problem, known as the facility location problem, has been studied from different perspectives, considering a number of different constraints.
Enrique García‐Galán   +2 more
wiley   +1 more source

[Cybersecurity and use of ICT in the health sector]. [PDF]

open access: yesAten Primaria
Cervera García A, Goussens A.
europepmc   +1 more source

Deacetylase inhibitors CM‐444 and CM‐1758 enhance chemotherapy response in AML via ALOX5

open access: yes
British Journal of Haematology, EarlyView.
Naroa Gimenez‐Camino   +7 more
wiley   +1 more source

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