Results 181 to 190 of about 583,034 (245)

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin   +3 more
wiley   +1 more source

Non‐Linear Threshold Effect of Dynamic Estimated Plasma Volume Status on Revealing In‐Hospital Mortality Risk in Sepsis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study evaluated the association between estimated plasma volume status (ePVS) and in‐hospital mortality in adult patients with sepsis from the MIMIC‐IV (v2.2) database. After excluding patients with early death, readmission, red blood cell transfusion, malignancy, or missing ePVS data, 17,403 patients meeting Sepsis‐3
Zhi‐An Si   +3 more
wiley   +1 more source

A comparative "report card" wellbeing assessment of 22 countries in the Global Flourishing Study. [PDF]

open access: yesDiscov Glob Soc
Lomas T   +12 more
europepmc   +1 more source

Femoral component internal rotation in functionally aligned robotic‐assisted total knee arthroplasty does not impair functional outcomes

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Femoral component internal rotation tightens the medial flexion gap and medialises femoral trochlea position, thus influencing patellofemoral tracking and function. Therefore, one of the tenets of mechanically aligned total knee arthroplasty (TKA) has been to avoid femoral component internal rotation relative to the transepicondylar ...
Andrew Philpott   +4 more
wiley   +1 more source

Agent‐Related Perceptions of Automated Versus Human Agents and the Role of Task‐Related Risk: A Meta‐Analysis

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT Firms often seek to replace human agents (HAs) with automated agents (AAs) for customer service, but customers still tend to react more negatively to AAs than to HAs. This meta‐analysis examines agent‐related perceptions (i.e., humanlikeness, warmth, and competence), which represent the key upstream customer reactions shaping downstream ...
Sandra Miederer   +3 more
wiley   +1 more source

A One-Year longitudinal study on Surrender to God assessed during addiction treatment. [PDF]

open access: yesAddict Behav Rep
Seesink HJ   +4 more
europepmc   +1 more source

Beyond Reality Avoidance: Unraveling the Paradox of Escapism Through Self‐Monitoring and Autonomy Mechanisms for Consumers' Life Satisfaction

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT This study introduces the Paradox of Escapism, exploring how the act of escaping reality can evolve from a short‐term avoidance strategy to a mechanism for self‐regulation and enhanced life satisfaction. Employing five rigorous, multimethod investigations, including qualitative interviews and sentiment analysis (Study 1), Structural Equation ...
Thamiris Magalhães de Sousa   +3 more
wiley   +1 more source

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