Results 31 to 40 of about 2,245,917 (288)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

No evidence of mid-flexion instability after robotic-assisted total knee arthroplasty as assessed by intraoperative pressure sensors

Arthroplasty
Purpose Mid-flexion instability has been identified as a cause for dissatisfaction following total knee arthroplasty (TKA). Robotic-assisted surgery using the Mako robot only allows for assessment of stability at 10° and 90°.
Mateo Armendariz, Baha John Tadros, Dermot Collopy, Gavin Clark   +3 more
doaj   +1 more source

Correction to: Does this lung nodule need urgent review? A discrete choice experiment of Australian general practitioners

BMC Pulmonary Medicine, 2020
Following publication of the original article [1], the authors flagged that the article had gone to publishing with errors in Tables 1-3.
P. Brownell, F. Piccolo, F. Brims, R. Norman, D. Manners   +4 more
doaj   +1 more source

Anterograde Injection of Alteplase Salvages Deep Inferior Epigastric Perforator Flap in Reconstructive Breast Surgery

Plastic and Reconstructive Surgery, Global Open, 2022
Summary:. The DIEP flap is currently considered the gold standard for autologous reconstructive breast surgery. Postoperative flap failure due to microvascular postanastomotic thrombotic occlusion is a rare but severe complication.
Julia M. Wimbauer, MD, Klemens M. Heinrich, MD, Karl Schwaiger, MD, Peter Pumberger, MD, Fabian Koeninger, MD, Gottfried Wechselberger, MD, MSc, Elisabeth Russe, MD   +6 more
doaj   +1 more source

About Gods, I Don\u27t Believe in None of That Shit, the Facts Are Backwards: Slaughterhouse\u27s Lyrical Atheism [PDF]

, 2016
Hip Hop group Slaughterhouse\u27s multi-membered, perversely holy quadrinity provides a fertile site for a pseudo-non-theological theological reading-a theology with and without god, that is, with god\u27s titular presence but bereft of any ethos of a ...
Bey, Marquis
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Prevalence of anxiety and associated factors among guardians of children admitted with severe malaria at Thyolo District Hospital in Malawi

South African Journal of Psychiatry
Background: Anxiety is a common psychological response among caregivers of children with severe illnesses, yet limited research has explored its prevalence and associated factors in guardians of children with severe malaria in Malawi.
Nixon Chidzere, Chimwemwe Munthali, George Chapweteka, Thandie Munthali, Patson Kumwenda, Blessings Chikasema, Esmie Mkwinda, Geldine Chironda   +7 more
doaj   +1 more source

Giant lobular capillary hemangioma of the breast

Journal of Pediatric Surgery Case Reports, 2019
Lobular capillary hemangioma or pyogenic granuloma is a benign vascular tumor of the skin or mucous membranes characterized by rapid growth and friable surface. It occurs at any age. The etiology remains unclear.
Assogba Léopold Azakpa, Essodina Ndayake, Irene Gonzalez-Rodilla, Florent Priuli   +3 more
doaj   +1 more source

Chronic haemothorax: an important cause of pleural effusion

Respirology Case Reports, 2021
We describe a case of chronic exudative pleural effusion in a patient initially referred with anorexia, weight loss, and past history of breast cancer, following multiple presentations with chest pain and dyspnoea.
David K. Z. Ching, Edward T. H. Fysh
doaj   +1 more source

Worship: the source and summit of faith [PDF]

, 1983
In worship God comes to serve his people with his gifts. Worship, as God\u27s service of us, is the source of faith. Worship is also the summit of faith as God lifts his people to himself, to the service of others, to a reconciliation with the natural ...
Pfatteicher, Philip H.
core   +1 more source