Results 31 to 40 of about 511,959 (307)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Collapse of underground galleries in gold-panning mines: Perception of stakeholders in the Doko Sub-Prefecture, Siguiri Prefecture, Republic of Guinea

Environmental & Socio-economic Studies
Artisanal gold mining is recognized as a long-standing activity in the Siguiri prefecture in general and the Doko sub-prefecture in particular. Despite its significant contribution to community development, it has disastrous consequences for both the ...
Diallo Moussa, Konaté Ahmed Amara, Sidibé Diaka   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Identifying and Comparing the Exploration Criteria at Sari Gunay Gold, Dalli Copper-Gold and Zarshuran Gold Deposits in Zagros Orogen

Journal of Economic Geology, 2023
There are important deposits such as Sari Gunay epithermal gold, Dalli porphyry copper-gold, and Zarshuran Carlin deposits with a few common exploration features in the Zagros metallogenic province of Iran. This study used geological maps, remote sensing,
Pouya Asadi Haroni, Omid Asghari, Mirsaleh Mirmohammadi , Hooshang Asadi Haroni   +3 more
doaj   +1 more source

Minerals in Afghanistan : the potential for gold [PDF]

, 2006
Gold has been worked in Afghanistan for centuries from many areas including Takhar province in the north and from Ghazni, Zabul, and Kandahar provinces in the south-west of the country.
Benham, Antony John, Coats, Stan
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Three-dimensional modeling and geostatistical structural analysis for ore deposit prospecting trend and wisdom mining: a case study in the Jiaoxibei gold field, China

Frontiers in Earth Science
The orientation of deep-seated orebodies was observed shifted from the northwest to north at the Xincheng deposit in the Jiaoxibei gold field during the mining operations.
Xiaoning Liu, Xiaoning Liu, Xiaoning Liu, Gongwen Wang, Gongwen Wang, Gongwen Wang, Gongwen Wang, Gongwen Wang, Jingyi Lv, Jingyi Lv, Yongming Peng, Xianyong Zhao   +11 more
doaj   +1 more source

Holographic microscopy for the three-dimensional exploration of light scattering from gold nanomarkers in biological media

, 2011
The 3D structure of light scattering from dark-field illuminated live 3T3 cells marked with 40 nm gold nanomarkers is explored. For this purpose, we use a high resolution holographic microscope combining the off-axis heterodyne geometry and the phase ...
Abboud, Marie, Desbiolles, Pierre, Gross, Michel, Joud, Fadwa, Verpillat, Frédéric   +4 more
core   +4 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source