Results 71 to 80 of about 511,959 (307)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Metallogenic potential and prospecting of orogenic gold deposits in the Shuihouling area of the Dabie Orogenic Belt: A geochemical evidence from stream sediment anomalies

Solid Earth Sciences
The Shuihouling ductile shear zone, located in the core of the Dabie Orogenic Belt spanning Anhui and Hubei provinces, is a key structural unit with notable mineral potential. Situated within the Wudang-Tongbai-Dabie Mo-REE-Au-Ag-Pb-Zn polymetallic belt,
Xiandong Luo, Lei Chen, Jinlai Tang, Xiaoyong Yang   +3 more
doaj   +1 more source

An evolving subduction-related magmatic system in the Masara Gold District, Eastern Mindanao, Philippines

Journal of Asian Earth Sciences: X, 2019
The Masara Gold District in Eastern Mindanao, Philippines, is one of the most prolific gold provinces in the Philippines. Recent district-scale mineral exploration makes it possible to undertake geologic and geochemical studies and thus to yield better ...
Alfred Elmer Buena, Barbie Ross B. Villaplaza, Betchaida D. Payot, Jillian Aira S. Gabo-Ratio, Noelynna T. Ramos, Decibel V. Faustino-Eslava, Karlo L. Queaño, Carla B. Dimalanta, Jenielyn T. Padrones, Kenichiro Tani, Walter W. Brown, Graciano P. Yumul, Jr.   +11 more
doaj   +1 more source

Social Indicators for Arctic Mining [PDF]

, 2011
This paper reviews and assesses the state of the data to describe and monitor mining trends in the pan-Arctic. It constructs a mining index and discusses its value as a social impact indicator and discusses drivers of change in Arctic mining.
Crow, Andrew, Haley, Sharman, Klick, Matthew, Schwoerer, Tobias, Szymoniak, Nick   +4 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Research on weak information extraction methods in the exploration of hidden Carlin-type gold deposits in southwestern Guizhou, China

Dizhi lixue xuebao
Objective  The southwestern Guizhou region is a concentrated distribution area of Carlin-type gold deposits in China, with superior geological conditions for gold mineralization and enormous potential for mineral exploration.
TAN Lijin, LIU Jianzhong, TAN Qinping, LI Songtao, SONG Weifang, LI Junhai, WANG Zepeng, XU Liangyi, ZHANG Bingqiang, LIU Ping, MENG Minghua   +10 more
doaj   +1 more source

Knowledge transfer inside the regional economic system: the case of eighty years of economic history of the Russian North-East [PDF]

Economic role of the knowledge transfer is studied on the example of the Russian North-East and its two basic branches that is exploration and mining which form the core of the regional economy (regional mining system).
Alexander Pelyasov, Igor Batsaev, Igor Golubenko, Nataliya Galtseva   +3 more
core  

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source