Results 91 to 100 of about 2,118 (251)

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

open access: yesAdvanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu   +7 more
wiley   +1 more source

Chemical characterization of heavy minerals and stream sediment of Betare-Oya gold district and implications for gold mineralization

open access: yesDiscover Chemistry
Stream sediment geochemical survey was carried out in Boyo, situated in Betare-Oya gold district. The study was aimed to determine the primary source of gold, mineralogy of heavy mineral concentrate, provenance, weathering conditions and tectonic setting.
Ndema Mbongué Jean-Lavenir   +2 more
doaj   +1 more source

The case for gold panning in Scotland [PDF]

open access: yes, 2014
In March 2014, the Hunterian at the University of Glasgow will hold an exhibition of gold in Scotland. Amongst the treasures on display will be the King's Gold Cup from the Leith races of 1751, Queen Victoria's gold collar of the Order of the Thistle, 'cloth of gold' from the tomb of Robert the Bruce, Bronze and Iron Age gold torcs (especially the ...
openaire  

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Investigation of Cough Cases in Burkina Faso: Epidemiological Profile and Environmental Factors Contributing to the November 2023 Outbreak

open access: yesHealth Research in Africa
Introduction. In Burkina Faso, the burden of acute and chronic respiratory diseases on the population remains high. Following a report of coughing cases in the village of Gomboussougou, an epidemiological investigation was conducted to assess the scale ...
Ouedraogo HS   +12 more
doaj   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

L’activité minière artisanale dans l’ouest du Kenya : entre dynamiques locales & dynamiques transfrontalières

open access: yesL'Espace Politique
This article highlights the specificity of Kakamega County – Western Kenya - in the context of the new gold rushes in Sub-Saharan Africa. Although Kakamega County shares borders with Tanzania and Uganda, it is characterized by national and local dynamics
Joseph Bohbot
doaj   +1 more source

Programmable Guest‐Induced 5‐Phase‐Transition Topological Reconstructions of Cobalt Formate Metal–Organic Frameworks

open access: yesAdvanced Science, EarlyView.
A reversible five‐phase topological cycle is achieved in a minimalist cobalt formate metal–organic framework. The amorphous phase functions as a programmable reactive hub, selectively reconstructing into four distinct crystalline architectures through cationic templates, humidity, or CO2.
Zhiyu Tao   +6 more
wiley   +1 more source

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